(3-Carboxypropyl)triphenylphosphonium bromide

ALDRICH/349720 - 98%

Synonym: (4-Hydroxy-4-oxobutyl)triphenylphosphonium bromide

CAS Number: 17857-14-6
Empirical Formula (Hill Notation): C₂₂H₂₂BrO₂P
Molecular Weight: 429.29
MDL Number: MFCD00274196
Linear Formula: HO₂C(CH₂)₃P(C₆H₅)₃Br
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-349720-25G	25 g	$99.30 1/EA	Add To Favorites
45-349720-100G	100 g	$307.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	98%
InChI	1S/C22H21O2P.BrH/c23-22(24)17-10-18-25(19-11-4-1-5-12-19,20-13-6-2-7-14-20)21-15-8-3-9-16-21;/h1-9,11-16H,10,17-18H2;1H
InChI key	NKVJKVMGJABKHV-UHFFFAOYSA-N
mp	244-247 °C (lit.)
reaction suitability	reaction type: C-C Bond Formation
SMILES string	[Br-].OC(=O)CCC[P+](c1ccccc1)(c2ccccc2)c3ccccc3

Application:

Reactant for preparation of:
• Piperamide analogs as histone deacetylase (HDAC) inhibitors with antitumor activity
• Boron-containing benzoxaboroles as antimalarial agents
• Methyl alkenyl quinolones as antimycobacterial agents
• Solandelactone E via Sharpless epoxidation, Taber cyclopropanation, chemoselective reductions and lithiation-borylation-allylation sequence
• Organotin compounds as antifungal agents
• Oleanolic acid derivatives as inhibitors of protein tyrosine phosphatase 1B for negative regulation of insulin pathway (a promising target for treatment of diabetes and obesity)
• 11-oxa prostaglandin analogs with ocular hypotensive activity

Packaging:

25, 100 g in glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	98%
mp	244-247 °C (lit.)
UNSPSC	12352002

To Order From a Quote