(S)-(−)-α,α-Diphenyl-2-pyrrolidinemethanol
ALDRICH/368199 - 99%
Synonym: (S)-(−)-2-(Diphenylhydroxymethyl)pyrrolidine; α,α-Diphenyl-L-prolinol
CAS Number: 112068-01-6
Empirical Formula (Hill Notation): C17H19NO
Molecular Weight: 253.34
MDL Number: MFCD00075506
Linear Formula: C17H19NO
Product Type: Chemical
| assay | 99% |
| form | solid |
| functional group | hydroxyl |
| phenyl | |
| InChI | 1S/C17H19NO/c19-17(16-12- |
| InChI key | OGCGXUGBDJGFFY-INIZCTEOSA |
| mp | 77-80 °C (lit.) |
| optical activity | [α]20/D −67°, c = 3 in chloroform |
| Quality Level | 200  |
| SMILES string | OC([C@@H]1CCCN1)(c2ccccc2 |
| Application: | (S)-(-)-α,α-Diphenyl-2-pyrr • DPPM reacts with catecholborane to form a spiroborate ester, which can be an efficient catalyst for the synthesis of enantiopure alcohols by borane reduction of acetophenone. • The catalyst generated in situ by reacting DPPM with borane-diethylaniline, can efficiently catalyze the enantioselective reduction of 2′-fluoroacetophenone. • Mesoporous SBA-15 silica functionalized with DPPM can catalyze the addition of diethylzinc to benzaldehyde to form (S)-1-phenyl-propanol. |
| Application: | Used to prepare the corresponding oxazaborolidines for the borane-mediated asymmetric reduction of ketones. |
| General description: | (S)-(-)-α,α-Diphenyl-2-pyrr |
| Packaging: | 1, 5 g in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P261 - P264 - P271 - P280 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 99% |
| mp | 77-80 °C (lit.) |
| UNSPSC | 12352005 |