1,4-Diisocyanatobutane
ALDRICH/371130 - 97.0%
Synonym: Tetramethylene diisocyanate
CAS Number: 4538-37-8
Empirical Formula (Hill Notation): C6H8N2O2
Molecular Weight: 140.14
MDL Number: MFCD00075559
Linear Formula: OCN(CH2)4NCO
Product Type: Chemical
| assay | 97.0% |
| bp | 102-104 °C/14 mmHg (lit.) |
| density | 1.105 g/mL at 25 °C (lit.) |
| form | liquid |
| InChI | 1S/C6H8N2O2/c9-5-7-3-1-2- |
| InChI key | OVBFMUAFNIIQAL-UHFFFAOYSA |
| SMILES string | O=C=NCCCCN=C=O |
| storage temp. | 2-8°C |
| Application: | 1,4-Diisocyanatobutanecan be used in the following fields: Tissue engineering -As a precursor to synthesize polyurethane composites which can be used as 3D scaffolds for tissue engineering, Contact lenses- As a cross-linking agent to prepare inorganic-organic hydrogel contact lenses for high refractive index ocular refractive correction biomaterial, Controlled drug delivery- As a chain extender to synthesize segmented polyurethanes for redox-sensitive controlled drug release systems. |
| General description: | 1,4-Diisocyanatobutane is a highly reactive compound with two isocyanate (-NCO) groups separated by a butane chain. It can undergo reactions such as urethane formation, crosslinking, and chain extension. It is widely used as a building block to synthesize polyurethane-based materials with excellent flexibility, impact resistance, and mechanical properties, making them useful in tissue engineering, contact lenses, biocompatible coatings, adhesives, foams, elastomers, and sealants. |
| Packaging: | 1, 5 g in glass bottle |
| Symbol |   GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 + H312 + H332 - H315 - H317 - H319 - H334 - H335 |
| Precautionary statements | P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 26-27-37/39 |
| RIDADR | UN 3334 |
| WGK Germany | WGK 3 |
| Flash Point(F) | 222.8 °F - closed cup |
| Flash Point(C) | 106 °C - closed cup |
| Purity | 97.0% |
| bp | 102-104 °C/14 mmHg (lit.) |
| Density | 1.105 g/mL at 25 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12162002 |