1,4-Diisocyanatobutane

ALDRICH/371130 - 97.0%

Synonym: Tetramethylene diisocyanate

CAS Number: 4538-37-8
Empirical Formula (Hill Notation): C₆H₈N₂O₂
Molecular Weight: 140.14
MDL Number: MFCD00075559
Linear Formula: OCN(CH₂)₄NCO
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-371130-1G	1 g	$178.00 1/EAAdd To Favorites		Add To Favorites
45-371130-5G	5 g	$669.00 1/EAAdd To Favorites		Add To Favorites

assay	97.0%
bp	102-104 °C/14 mmHg (lit.)
density	1.105 g/mL at 25 °C (lit.)
form	liquid
InChI	1S/C6H8N2O2/c9-5-7-3-1-2-4-8-6-10/h1-4H2
InChI key	OVBFMUAFNIIQAL-UHFFFAOYSA-N
Quality Level	200
SMILES string	O=C=NCCCCN=C=O
storage temp.	2-8°C

Application:	1,4-Diisocyanatobutanecan be used in the following fields: Tissue engineering -As a precursor to synthesize polyurethane composites which can be used as 3D scaffolds for tissue engineering, Contact lenses- As a cross-linking agent to prepare inorganic-organic hydrogel contact lenses for high refractive index ocular refractive correction biomaterial, Controlled drug delivery- As a chain extender to synthesize segmented polyurethanes for redox-sensitive controlled drug release systems.
General description:	1,4-Diisocyanatobutane is a highly reactive compound with two isocyanate (-NCO) groups separated by a butane chain. It can undergo reactions such as urethane formation, crosslinking, and chain extension. It is widely used as a building block to synthesize polyurethane-based materials with excellent flexibility, impact resistance, and mechanical properties, making them useful in tissue engineering, contact lenses, biocompatible coatings, adhesives, foams, elastomers, and sealants.
Packaging:	1, 5 g in glass bottle

Symbol	GHS07,GHS08
Signal word	Danger
Hazard statements	H302 + H312 + H332 - H315 - H317 - H319 - H334 - H335
Precautionary statements	P261 - P264 - P280 - P301 + P312 - P302 + P352 + P312 - P305 + P351 + P338
Hazard Codes	Xn
Risk Statements	20/21/22-36/37/38
Safety Statements	26-27-37/39
RIDADR	UN 3334
WGK Germany	WGK 3
Flash Point(F)	222.8 °F - closed cup
Flash Point(C)	106 °C - closed cup