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6,6′-Dithiodinicotinic acid

ALDRICH/373605 - technical grade, 85%

Synonym: Bis[3-Carboxypyridine] 6,6′-disulfide; Bis[3-carboxypyridine] 6,6′-disulfide

CAS Number: 15658-35-2
Empirical Formula (Hill Notation): C12H8N2O4S2
Molecular Weight: 308.33
EC Number: 239-729-6
MDL Number: MFCD00006454
Linear Formula: C12H8N2O4S2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-373605-5G 5 g
 $127.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 373605-5G

 

assay 85%
form solid
grade technical grade
InChI 1S/C12H8N2O4S2/c15-11(16)7-1-3-9(13-5-7)19-20-10-4-2-8(6-14-10)12(17)18/h1-6H,(H,15,16)(H,17,18)
InChI key GSASOFRDSIKDSN-UHFFFAOYSA-N
mp 263-265 °C (lit.)
SMILES string OC(=O)c1ccc(SSc2ccc(cn2)C(O)=O)nc1
Application: 6,6′-Dithiodinicotinic acid may be employed as:
• specific thiol blocker to investigate the radioprotective effect of mercaptoethylamine on the thiol level of the outer cell membrane of the Ehrlich ascites tumor cells
• modifier to investigate the polar microenvironment around the reactive Cys283 of rabbit muscle creatine kinase
• dipyridyl-dithio substrate to evaluate the protein disulfide-thiol interchange activity of the auxin stimulated NADH: protein disulfide reductase (NADH oxidase) of soybean plasma membranes
• water-soluble reagent in a study for introducing, in buffered saline, a reactive sulfhydryl group on water-soluble molecules bearing an alkyl-amino group
• chromogen for sulfhydryl groups in the Ellman method for cholinesterase determinations
• spectrophotometric determination of thiols and of total glutathione in human blood
General description: 6,6′-Dithiodinicotinic acid is reported as sulphydryl reagent. 6,6′-Dithiodinicotinic acid is reported to react with thiols, to afford a disulfide and 6-mercaptonicotinic acid. Interaction of 6,6′-dithiodinicotinic acid with the homogenates of Ehrlich ascites cells has been reported.
Packaging: 5 g in glass bottle
Purity 85%
mp 263-265 °C (lit.)
UNSPSC 12352100

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