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2,8-Quinolinediol

ALDRICH/37640 - ≥99.0% (HPLC)

Synonym: 2,8-Dihydroxyquinoline

CAS Number: 15450-76-7
Empirical Formula (Hill Notation): C9H7NO2
Molecular Weight: 161.16
MDL Number: MFCD00216696
Linear Formula: C9H7NO2
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-37640-1G-F 1 g
$44.60
1/EA
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assay ≥99.0% (HPLC)
form powder
InChI 1S/C9H7NO2/c11-7-3-1-2-6-4-5-8(12)10-9(6)7/h1-5,11H,(H,10,12)
InChI key ZXZKYYHTWHJHFT-UHFFFAOYSA-N
mp ~290 °C (dec.)
SMILES string Oc1ccc2cccc(O)c2n1
Application: 2,8-Quinolinediol is suitable for use as standard in a study to identify the urinary metabolites for the toxicity related processes and pathogenesis induced by doxorubicin (DOX) to rats by online and off-line LC-MS techniques. It may be used as starting reagent for the preparation of two powerful β2-adrenergic receptor agonists, used for the treatment of asthma:
• Procaterol
• Indacaterol
General description: 2,8-Quinolinediol is a quinolone derivative. It has been reported as metabolite of 8-hydroxyquinoline-N-oxide in rabbits. Synthesis of 2,8-quinolinediol has been reported. It is reported as one of the six possible forms of 8-hydroxycarbostyril. It has been detected as new UV-absorbing compound (UAC) in cow milk and its structure was elucidated using HRMS and by 1H, 13C and 1H ×13C NMR.It is also known as 8-hydroxycarbostyril or 8-hydroxyquinolin-2(1H)-one.
General description: 8-hydroxyquinolin-2(1H)-one has been reported as the tautomeric form of 2,8-quinolinediol. 2,8-Quinolinediol (2,8-Dihydroxyquinoline) has been identified as one of the metabolite of quinolone formed in the culture medium of gram-negative bacteria, Pseudomonas stutzeri.
Packaging: 1, 5 g in glass bottle
Purity ≥99.0% (HPLC)
mp ~290 °C (dec.)
UNSPSC 12352100

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