N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate
ALDRICH/385530 - 97%
Synonym: O-(N-Succinimidyl)-N,N,N′,N′-tetramethyluronium tetrafluoroborate; TSTU
CAS Number: 105832-38-0
Empirical Formula (Hill Notation): C9H16BF4N3O3
Molecular Weight: 301.05
MDL Number: MFCD00077875
Linear Formula: C9H16BF4N3O3
Product Type: Chemical
| application(s) | peptide synthesis |
| assay | 97% |
| functional group | amine |
| imide | |
| InChI | 1S/C9H16N3O3.BF4/c1-10(2) |
| InChI key | YEBLHMRPZHNTEK-UHFFFAOYSA |
| mp | 198-201 °C (lit.) |
| Quality Level | 300  |
| reaction suitability | reaction type: Coupling Reactions |
| SMILES string | F[B-](F)(F)F.CN(C)C(ON1C |
| storage temp. | 2-8°C |
| Application: | N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate may be used in the synthesis of N-succinimidyl 4-[18F]fluorobenzoate ([18F]SFB), a 18F-labeled agent used for labeling biomarkers. it may also be used for the activation of carboxylic group of C16-chained alkanethiols that are used in developing surface plasmon resonance (SPR) sensors. |
| Application: | Reactant for: Linking sensor molecules with amino groups to amino functionalized AFM tips Reactant for synthesis of: A polymer supported oranotin reagent for prosthetic group labeling of biological macromolecules with radioiodine L-Rhamnose antigen Fluorinated rhodamines for optical microscopy and nanoscopy c(RGDyK) targeted SN38 prodrug Polyelectrolytes for thin film construction |
| General description: | N,N,N′,N′-Tetramethyl-O-(N-succinimidyl)uronium tetrafluoroborate is commonly used for the conversion of carboxylic acid into the corresponding N-hydroxysuccinimidyl (NHS) ester. |
| Packaging: | 1, 5 g in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 97% |
| mp | 198-201 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352107 |