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(2-Hydroxypropyl)-α-cyclodextrin

ALDRICH/390690 - average Mw ~1,180

Synonym: α‐HPCD; 2OHpαCD; 2‐hydroxypropyl‐α‐CD; HPαCD; HP-α-CD

CAS Number: 128446-33-3
MDL Number: MFCD00197866
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-390690-5G 5 g
 $68.50
1/EA		 Add To Favorites
45-390690-25G 25 g
 $221.00
1/EA		 Add To Favorites

 

extent of labeling 0.6 molar substitution
form powder
InChI 1S/C54H96O36/c1-19(55)7-73-13-25-43-31(61)37(67)49(79-25)86-44-26(14-74-8-20(2)56)81-51(39(69)33(44)63)88-46-28(16-76-10-22(4)58)83-53(41(71)35(46)65)90-48-30(18-78-12-24(6)60)84-54(42(72)36(48)66)89-47-29(17-77-11-23(5)59)82-52(40(70)34(47)64)87-45-27(15
InChI key PMPYGZCSMCXHTA-WABPNHHRSA-N
mol wt average Mw ~1,180
mp 245 °C (dec.) (lit.)
optical activity [α]20/D +125°, c = 1 in H2O
Quality Level 100 
SMILES string O1[C@H]2O[C@@H]([C@@H](O[C@H]3O[C@@H]([C@@H](O[C@H]4O[C@@H]([C@@H](O[C@H]5O[C@@H]([C@@H](O[C@H]6O[C@@H]([C@@H](O[C@H]7O[C@@H]([C@@H]1[C@H]([C@@H]7O)O)COCC(O)C)[C@H]([C@@H]6O)O)COCC(O)C)[C@H]([C@@H]5O)O)COCC(O)C)[C@H]([C@@H]4O)O)COCC(O)C)[C@H]([C@@H]3O)O)C
Application: • (2-Hydroxypropyl)-α-cyclodextrin can be used as a chiral selector to resolve tryptophan racemate by capillary electrophoresis.
• It can be used to synthesize biodegradable polyrotaxanes for fabricating blood-contacting devices.
• Co-polymer based on (2-hydroxypropyl)-α-cyclodextrin cross-linked with polyethylenimine can be used as a gene delivery vector.
• It can also be used as stabilizer for antibacterial iodine formulations, as it forms a stable inclusion complex with iodine and improves aqueous solubility.

General description: (2-Hydroxypropyl)-α-cyclodextrin is a hydroxyalkyl derivative of cyclodextrin, which is generally used as a substitute of α-cyclodextrin for potential application in food, cosmetics and pharmaceutical industries. It may be used as a parenteral drug carrier on account of its attractive characteristics such as: a greater extent of solubility in water, high dissolution capacity for weakly soluble analytes, and low toxicity.
Packaging: 5, 25 g in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
mp 245 °C (dec.) (lit.)
UNSPSC 12352201

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