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(2-Hydroxypropyl)-γ-cyclodextrin

ALDRICH/390704 - extent of labeling: 0.6 molar substitution

Synonym: HP-γ-CD; HPGCD; HGC

CAS Number: 128446-34-4
MDL Number: MFCD16621721
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-390704-5G 5 g
 $86.50
1/EA		 Add To Favorites
45-390704-25G 25 g
 $185.00
1/EA		 Add To Favorites

 

extent of labeling 0.6 molar substitution
form powder
InChI 1S/C51H88O38/c1-14(56)8-73-11-21-42-29(64)36(71)50(81-21)85-40-19(6-54)79-48(34(69)27(40)62)89-44-23(13-75-10-16(3)58)82-51(37(72)30(44)65)86-41-20(7-55)78-47(33(68)26(41)61)88-43-22(12-74-9-15(2)57)80-49(35(70)28(43)63)84-39-18(5-53)76-45(31(66)24(39)59)83-38-17(4-52)77-46(87-42)32(67)25(38)60/h14-72H,4-13H2,1-3H3/t14?,15?,16?,17-,18-,19-,20-,21-,22-,23-,24-,25-,26-,27-,28-,29-,30-,31-,32-,33-,34-,35-,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-/m0/s1
InChI key ODLHGICHYURWBS-RYJYQAAZSA-N
mol wt average Mw ~1,580
optical activity [α]20/D +145°, c = 1 in H2O
Quality Level 100 
SMILES string O1[C@@H]2O[C@H]([C@H](O[C@@H]3O[C@H]([C@H](O[C@@H]4O[C@H]([C@H](O[C@@H]5O[C@H]([C@H](O[C@@H]6O[C@H]([C@H](O[C@@H]7O[C@H]([C@H](O[C@@H]8O[C@H]([C@H]1[C@H]([C@@H]8O)O)COCC(O)C)[C@H]([C@@H]7O)O)CO)[C@H]([C@@H]6O)O)COCC(O)C)[C@H]([C@@H]5O)O)CO)[C@H]([C@@H]4O)
Application: (2-Hydroxypropyl)-γ-cyclodextrin may be used:
• As a mobile phase additive in the study of the host-guest interaction with organic low molecular mass compounds prior to their quantification using reversed phase-high performance liquid chromatography (RP-HPLC) technique.
• As a chiral surfactant for the analysis of econazole by micellar electrokinetic chromatography (MEKC).
• As an analytical standard for the determination of the analyte in biological samples by HPLC.
• As a chiral selector for the identification of propiconazole by MEKC.
General description: (2-Hydroxypropyl)-γ-cyclodextrin belongs to the class of cyclodextrin derivatives, which exhibit a greater extent of solubility in water compared to their parent compounds. It is widely used in parenteral formulations and solid dosage forms to aid in the improvement of their stability, dissolution, bioavailability, etc.
Packaging: 5, 25 g in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
UNSPSC 12352201

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