4-(Dimethylamino)pyridine, polymer-bound
ALDRICH/39410 - extent of labeling: ~3.0 mmol/g "DMAP" loading, matrix crosslinked with 2% DVB
Synonym: 4-
CAS Number: 82942-26-5
Empirical Formula (Hill Notation): C8H8
Molecular Weight: 104.15
MDL Number: MFCD04041220
Linear Formula: C8H8
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 39410-5G.
| anion traces | chloride (Cl-): ≤5000 mg/kg |
| extent of labeling | ~3.0 mmol/g "DMAP" loading |
| matrix | crosslinked with 2% DVB |
| Quality Level | 200  |
| reaction suitability | reaction type: solution phase peptide synthesis |
| Application: | Polymer-bound 4-(dimethylamino)pyridine is used as a supported base in the Michael addition and nitrous acid elimination process step involved in the synthesis of thiophene-2-carboxylates using β-nitroacrylates as starting materials, under a general and efficient continuous flow-based protocol. It also serves as a supported catalyst in the preparation of ω-nitro esters starting from cyclic 2-nitro ketones under solid heterogeneous catalysis.(5) |
| General description: | Polymer-bound 4-(dimethylamino)pyridine is used for improved derivatization of chiral and achiral aliphatic amines, amino alcohols and amino acids. |
| Other Notes: | Polymer supported, recyclable acylation catalyst |
| Other Notes: | Polymer supported, recyclable acylation catalystcitationcitationc |
| Packaging: | 5, 25 g in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| UNSPSC | 12352128 |