N-Maleoyl-β-alanine
ALDRICH/394815 - 97%
Synonym: 3-Maleimidopropionic acid; N-
CAS Number: 7423-55-4
Empirical Formula (Hill Notation): C7H7NO4
Molecular Weight: 169.13
MDL Number: MFCD00043030
Linear Formula: C7H7NO4
Product Type: Chemical
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12 Principles of Green Chemistry: Principle 3—Less Hazardous Chemical Syntheses. This product manufacturing process was designed with lesser toxicity to human health and the environment.
12 Principles of Green Chemistry: Principle 5—Safer Solvents and Auxiliaries. This product utilizes reduced volumes of auxiliary substances that are less hazardous.
12 Principles of Green Chemistry: Principle 12—Inherently Safer Chemistry for Accident Prevention. This product utilizes safer chemistry to minimize the potential for chemical accidents, including releases, explosions and fires.
| assay | 97% |
| form | powder |
| greener alternative category |  , Re-engineered |
| greener alternative product characteristics | Less Hazardous Chemical Syntheses Safer Solvents and Auxiliaries Inherently Safer Chemistry for Accident Prevention Learn more about the Principles of Green Chemistry . |
| greener alternative product score | old score: 18 new score: 7 Find out more about DOZN™ Scoring |
| InChI | 1S/C7H7NO4/c9-5-1-2-6(10) |
| InChI key | IUTPJBLLJJNPAJ-UHFFFAOYSA |
| mp | 103-106 °C (lit.) |
| SMILES string | OC(=O)CCN1C(=O)C=CC1=O |
| storage temp. | 2-8°C |
| sustainability | Greener Alternative Product |
| Application: | N-Maleoyl-β-alanine (3-maleimidopropanoic acid, N-(2-carboxyethyl)maleimid • To decrease the biotin binding affinity of Avd(S16C) (avidin with a single point mutation S16C). • As a side chain reactive agent to modify tryptic peptides that result in mass shifts indicating the presence of cysteine residues. • To preblock Xenopus laevis oocytes for exposed cysteines used as an expression system in the study of conformational changes in cASIC1a Receptors. It may be used in the following studies: • As a protective agent for keratin fiber in high temperature process. • As a non-cleavable maleimido moiety during the synthesis of tetrawalled molecular umbrella-octaarginine conjugates. • Synthesis of organotin carboxylates of N-Maleoyl-β-alanine. • To functionalize the gold surfaces to interact with cysteine-modified peptide. • Preparation of cross-linked dextran–poly(ethylene glycol) hydrogel substrate. |
| General description: | N-Maleoyl-β-alanine (3-maleimidopropanoic acid) is an aliphatic N-substituted maleimide. It is one of the component of the stabilizing solution for EC145 (a folate-targeted vinca alkaloid conjugate) used in rodent pharmacokinetic studies. |
| General description: | We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Less Hazardous Chemical Syntheses”, "Safer Solvents and Auxiliaries" and “Inherently Safer Chemistry for Accident Prevention”. Click here to view its DOZN scorecard. |
| Packaging: | 1 g in glass bottle |
| Packaging: | 250 mg in glass bottle |
| Packaging: | Bottomless glass bottle. Contents are inside inserted fused cone. |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 97% |
| mp | 103-106 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352100 |