Polyethylenimine, branched
ALDRICH/408719 - average Mw ~800 by LS, average Mn ~600 by GPC
Synonym: PEI; ethylenediamine branched
CAS Number: 25987-06-8
MDL Number: MFCD00084427
Linear Formula: H(NHCH2CH2)nNH2
Product Type: Chemical
density | 1.050 g/mL at 25 °C |
form | viscous liquid |
InChI | 1S/C2H8N2.C2H5N/c3-1-2-4; |
InChI key | SFLOAOINZSFFAE-UHFFFAOYSA |
mol wt | average Mn ~600 by GPC |
average Mw ~800 by LS | |
refractive index | n |
Application: | Branched PEI can be used as a precursor to synthesize conjugated polyplexes for efficient gene transfection. Conjugation of PEI with Jeffamine polyether and guanidinylation of the amino groups of PEI reduce the cytotoxicity of the polyplexes and protect them from aggregation in the presence of serum proteins. Bamboo charcoal impregnated with PEI can be used as a CO2 adsorbent. Numerous amino groups present in PEI can react with CO2 due to acid-alkali interaction and enhance the adsorption capacity of bamboo charcoal. It can also be used to prepare cross-linked water-soluble polymers with high coordination capabilities towards organic drug molecules. |
Features and Benefits: | • Branched PEI has better complexation and buffering capacity. • High ion exchange capacity and affinity toward proteins. • SignificantDNA transfer efficiency. |
General description: | Polyethyleneimine is a hydrophilic polymerwidely used as a non-viral synthetic vector for invivo delivery of therapeutic nucleic acids. Owing to its excellentphysicochemical properties, it is applied in many fields like the separationand purification of proteins, carbon dioxide absorption, drug carriers,effluent treatment, and biological labels. |
Packaging: | 1 L in glass bottle |
Packaging: | 100, 250 mL in glass bottle |
Physical form: | Branched polymer |
Symbol | GHS05,GHS07,GHS09 |
Signal word | Danger |
Hazard statements | H302 - H318 - H411 |
Precautionary statements | P273 - P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310 |
Hazard Codes | Xn |
Risk Statements | 22-41-43-52/53 |
Safety Statements | 26-36/37/39-61 |
RIDADR | NONH for all modes of transport |
WGK Germany | WGK 3 |
Flash Point(F) | 356.0 °F |
Flash Point(C) | 180 °C |
Density | 1.050 g/mL at 25 °C |
Refractive Index | n |
UNSPSC | 12162002 |