Diethyl (bromodifluoromethyl)phosphonate
ALDRICH/411361 - 96%
Synonym: (Bromodifluoromethyl)
CAS Number: 65094-22-6
Empirical Formula (Hill Notation): C5H10BrF2O3P
Molecular Weight: 267.01
MDL Number: MFCD00069118
Linear Formula: BrCF2P(O)(OC2H5)2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 411361-5G
| assay | 96% |
| bp | 40-41 °C/0.05 mmHg (lit.) |
| density | 1.503 g/mL at 25 °C (lit.) |
| form | liquid |
| functional group | bromo |
| fluoro | |
| phosphonate | |
| InChI | 1S/C5H10BrF2O3P/c1-3-10-1 |
| InChI key | QRADKVYIJIAENZ-UHFFFAOYSA |
| Quality Level | 100  |
| reaction suitability | reaction type: C-C Bond Formation |
| refractive index | n |
| SMILES string | CCOP(=O)(OCC)C(F)(F)Br |
| Application: | Reactant for: • Preparation of phosphopeptide mimetic prodrugs targeted to Src homology 2 (SH2) domain of signal transducer and activator of transcription 3 (Stat3) • Synthesis of Mycobacterium tuberculosis protein tyrosine phosphatase inhibitory difluoromethylphosphonic acid derivatives via multi step synthesis with Suzuki coupling and resolution as key steps • P-C bond cleavage on basic hydrolysis • Preparation of a prodrug for intracellular delivery of protein tyrosine phosphatase 1B (PTP1B) inhibitor (nonhydrolyzable difluoromethylphosphonate moiety) |
| Packaging: | 5 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 96% |
| bp | 40-41 °C/0.05 mmHg (lit.) |
| Density | 1.503 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352108 |