1,3-Dimethyl-3,4,5,6-tetrahydro-2(1H)-pyrimidinone
ALDRICH/41661 - absolute, over molecular sieve (H2O ≤0.05%), ≥99.0% (GC)
Synonym: 1,3-
CAS Number: 7226-23-5
Empirical Formula (Hill Notation): C6H12N2O
Molecular Weight: 128.17
EC Number: 230-625-6
MDL Number: MFCD00006550
Linear Formula: C6H12N2O
Product Type: Chemical
| assay | ≥99.0% (GC) |
| bp | 146 °C/44 mmHg (lit.) |
| density | 1.06 g/mL at 25 °C (lit.) |
| form | liquid |
| grade | absolute |
| InChI | 1S/C6H12N2O/c1-7-4-3-5-8( |
| InChI key | GUVUOGQBMYCBQP-UHFFFAOYSA |
| quality | over molecular sieve (H2O ≤0.05%) |
| refractive index | n |
| n |
|
| SMILES string | CN1CCCN(C)C1=O |
| Application: | 1,3-Dimethyl-3,4,5,6-tetr • Solvent in the synthesis of 1-aryl-3,4,5-substituted pyrazoles by cyclocondensation of 1,3-diketones with arylhydrazine hydrochlorides. • Chelating solvent in the trifluoromethylation of activated and non-activated halogenated double bonds. • Ligand in ortho-alkylation of secondary benzamide catalyzed by cobalt. |
| Other Notes: | Aprotic, dipolar solvent, which is an excellent replacement of the carcinogenic HMPA as cosolvent for highly reactive nucleophiles and bases. High Z-selectivity in enolate formation; DMPU was shown to be non-mutagenic and safe. |
| Packaging: | 1 L in Sure/Seal™ |
| Packaging: | 250 mL in Sure/Seal™ |
| Symbol |    GHS05,GHS07,GHS08 |
| Signal word | Danger |
| Hazard statements | H302 - H318 - H361f |
| Precautionary statements | P201 - P280 - P301 + P312 + P330 - P305 + P351 + P338 + P310 - P308 + P313 |
| Hazard Codes | Xn |
| Risk Statements | 22-41-43-62 |
| Safety Statements | 23-26-36/37/39 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 1 |
| Flash Point(F) | 249.8 °F - DIN 51758 |
| Flash Point(C) | 121 °C - DIN 51758 |
| Purity | ≥99.0% (GC) |
| bp | 146 °C/44 mmHg (lit.) |
| Density | 1.06 g/mL at 25 °C (lit.) |
| Refractive Index | n |
| UNSPSC | 12352115 |