Boron tribromide
ALDRICH/419508 - ReagentPlus®, ≥99%
Synonym: Tribromoboron
CAS Number: 10294-33-4
Empirical Formula (Hill Notation): BBr3
Molecular Weight: 250.52
EC Number: 233-657-9
MDL Number: MFCD00011312
Linear Formula: BBr3
Product Type: Chemical
| assay | ≥99% |
| bp | ~90 °C (lit.) |
| color | colorless to amber |
| density | 2.60 g/mL at 20 °C (lit.) |
| InChI | 1S/BBr3/c2-1(3)4 |
| InChI key | ILAHWRKJUDSMFH-UHFFFAOYSA |
| mp | −46 °C (lit.) |
| product line | ReagentPlus® |
| SMILES string | BrB(Br)Br |
| vapor density | 8.6 (vs air) |
| vapor pressure | 40 mmHg ( 14 °C) |
| Application: | Reactant for preparation of: • Drug intermediate 6-nitro-L-DOPA • Luminescent polystyrene derivatives with sterically protected carbazolylborane moieties • High-quality boron-doped graphene via Wurtz-type reductive coupling reaction • Mercapto-(+)-methamphet • Micrometer-sized organic molecule-DNA hybrid structures • Borane complexes via electrophilic aromatic borylation reactions • A 5-HT2C receptor agonist • Biphenyl-derivatives possessing tertiary amino groups as β-secretase(BACE1) inhibitors for the treatment of Alzheimer′s disease • A highly near-IR region fluorescent p-extended boron aza-dipyrromethene moiety unit • Tetrahydroisoquinoline derivatives via intramolecular cyclization of methoxy-substituted N-phenethylimides |
| Application: | Used to cleave aryl methyl ethers in a synthesis of a benzopyranobenzopyran from a coumarin scaffold. |
| General description: | Boron tribromide is a strong Lewis acid generally employed in the deprotection of -OH and -NH groups. It is a moisture-sensitive liquid, which is also used to cleave esters or ethers into alkyl bromides. |
| Legal Information: | ReagentPlus is a registered trademark of Merck KGaA, Darmstadt, Germany |
| Packaging: | 4×25, 100, 500 g in Sure/Seal™ |
| Symbol |   GHS05,GHS06 |
| Signal word | Danger |
| Hazard statements | H300 + H330 - H314 |
| Precautionary statements | P260 - P270 - P280 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | T+,C |
| Risk Statements | 14-26/28-35 |
| Safety Statements | 9-26-28-36/37/39-45 |
| RIDADR | UN 2692 8 / PGI |
| WGK Germany | WGK 3 |
| Flash Point(F) | 196.3 °F |
| Flash Point(C) | 91.3 °C |
| Supplemental Hazard Statements | EUH014 |
| Purity | ≥99% |
| bp | ~90 °C (lit.) |
| mp | −46 °C (lit.) |
| Density | 2.60 g/mL at 20 °C (lit.) |
| UNSPSC | 12352101 |