6-Hydroxyflavanone
ALDRICH/419796 - 99%
CAS Number: 4250-77-5
Empirical Formula (Hill Notation): C15H12O3
Molecular Weight: 240.25
MDL Number: MFCD00017485
Linear Formula: C15H12O3
Product Type: Chemical
| assay | 99% |
| form | solid |
| InChI | 1S/C15H12O3/c16-11-6-7-14 |
| InChI key | XYHWPQUEOOBIOW-UHFFFAOYSA |
| mp | 220-222 °C (dec.) (lit.) |
| SMILES string | Oc1ccc2OC(CC(=O)c2c1)c3cc |
| Application: | 6-Hydroxyflavanone (6-HF) has been used for the enantiomeric separation of flavonoids using polysaccharide-based chiral stationary phases by nano-liquid chromatography (nano-LC). Racemic 6-HF may be used in the synthesis of 6-propionoxy-flavanone (6-PF). 6-HF may be employed as synthetic flavone to investigate the mechanism of tumor necrosis factor-related apoptosis-inducing ligand (TRAIL) induced cytotoxic and apoptotic effects in HeLa cancer cells. |
| General description: | 6-Hydroxyflavanone is a flavonoid. Its biotransformation by Aspergillus niger strains have been described. Crystal structure of S and R enantiomers of 6-hydroxyflavanone has been reported to have four crystallographic sites of the unit cell in an approximate 3:1/1:3 ratio. It was identified as a metabolite of flavnone on incubation with rat liver microsomes by positive ion electrospray LC/MS analysis. |
| Packaging: | 1 g in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 99% |
| mp | 220-222 °C (dec.) (lit.) |
| UNSPSC | 12352100 |