4,5-Dimethoxy-2-nitrobenzyl chloroformate

ALDRICH/420069 - 97%

Synonym: 6-Nitroveratryl chloroformate; 6-Nitroveratryloxycarbonyl chloride; NVOC chloride; NVOC-Cl

CAS Number: 42855-00-5
Empirical Formula (Hill Notation): C₁₀H₁₀ClNO₆
Molecular Weight: 275.64
MDL Number: MFCD00143507
Linear Formula: ClCO₂CH₂C₆H₂(OCH₃)₂NO₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-420069-1G	1 g	$230.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 420069-1G.

Properties
Descriptions
Safety Info.
Basic Data

application(s)	peptide synthesis
assay	97%
form	powder
InChI	1S/C10H10ClNO6/c1-16-8-3-6(5-18-10(11)13)7(12(14)15)4-9(8)17-2/h3-4H,5H2,1-2H3
InChI key	RWWPKIOWBQFXEE-UHFFFAOYSA-N
mp	125 °C (dec.) (lit.)
SMILES string	COc1cc(COC(Cl)=O)c(cc1OC)[N+]([O-])=O
storage temp.	2-8°C

Application:

4,5-Dimethoxy-2-nitrobenzyl chloroformate (NVOC-Cl) is a photolabile protecting reagent, commonly used in peptide or nucleotide synthesis to protect amines and hydroxyl groups. General applications are:
• Preparation of inactive, caged protein conjugates which can be activated by irradiating near-ultraviolet light.
• Solid-phase synthesis of base-sensitive S-acylthioethyl (SATE)-prooligonucleotides.
• Modification of surface properties by introducing photocleavable NVOC moiety into chitosan to control cell attachment.

Packaging:

1 g in glass bottle

Symbol	GHS05
Signal word	Danger
Hazard statements	H314
Precautionary statements	P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P305 + P351 + P338
Hazard Codes	C
Risk Statements	34-37
Safety Statements	26-36/37/39-45
RIDADR	UN 3261 8 / PGII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	97%
mp	125 °C (dec.) (lit.)
Storage Temp.	2-8°C
UNSPSC	12352101

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