2-Chloro-N-(hydroxymethyl)acetamide

ALDRICH/422835 - 98%

CAS Number: 2832-19-1
Empirical Formula (Hill Notation): C₃H₆ClNO₂
Molecular Weight: 123.54
EC Number: 220-598-9
MDL Number: MFCD00021961
Linear Formula: ClCH₂CONHCH₂OH
Product Type: Chemical

Catalog Number	PKG Qty.	Price	Quantity


45-422835-5G	5 g	$53.30 1/EA		Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	98%
InChI	1S/C3H6ClNO2/c4-1-3(7)5-2-6/h6H,1-2H2,(H,5,7)
InChI key	TXNSZCSYBXHETP-UHFFFAOYSA-N
mp	100-105 °C (lit.)
SMILES string	OCNC(=O)CCl

Application:	2-Chloro-N-(hydroxymethyl)acetamide (N-hydroxymethylchloroacetamide) may be used as a reagent in the synthesis of 1-(aminomethyl)-2-methoxynaphthalene hydrochloride and as a amidomethylating reagent for N,N-dialkylanilines (Tscherniac-Einhorn reaction).
General description:	2-Chloro-N-(hydroxymethyl)acetamide (N-methylolchloracetamide) is a N-hydroxymethyl derivative of chloroacetamide. One of the method reported for its synthesis is by the reaction of 2-chloracetamide with formaldehyde. It has been reported to be a formaldehyde releaser and an infrequent sensitizer to formaldehyde contact allergy. Influence of short and prolonged exposure of 2-chloro-N-(hydroxymethyl)acetamide (as formaldehyde donor/releaser) on lymph node responses has been investigated.
Packaging:	5 g in glass bottle

Symbol	GHS05
Signal word	Danger
Hazard statements	H314
Precautionary statements	P280 - P305 + P351 + P338 - P310
Hazard Codes	C
Risk Statements	34
Safety Statements	26-27-36/37/39-45
RIDADR	UN 3261 8 / PGII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	98%
mp	100-105 °C (lit.)
UNSPSC	12352100

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