4-Aminothiophenol
ALDRICH/422967 - ≥97.0%
Synonym: 4-Aminobenzenethiol; 4-Aminophenyl mercaptan; 4-Mercaptoaniline
CAS Number: 1193-02-8
Empirical Formula (Hill Notation): C6H7NS
Molecular Weight: 125.19
EC Number: 214-763-4
MDL Number: MFCD00007880
Linear Formula: H2NC6H4SH
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 422967-5G
| assay | ≥97.0% |
| bp | 140-145 °C/16 mmHg (lit.) |
| InChI | 1S/C6H7NS/c7-5-1-3-6(8)4- |
| InChI key | WCDSVWRUXWCYFN-UHFFFAOYSA |
| mp | 37-42 °C (lit.) |
| Quality Level | 100  |
| SMILES string | Nc1ccc(S)cc1 |
| storage temp. | 2-8°C |
| Application: | 4-Aminothiophenol (4-ATP) was employed as bifunctional molecule to functionalize gold nanoparticles (NPs) used in surface-enhanced Raman spectroscopy (SERS) detection of thrombin by protein recognition. It may be used in the following studies: • As a water insoluble ligand in the synthesis of pectin–4-aminothiophenol conjugates. • To functionalize gold nanorods (GNR) in the development of GNR nitrite sensor. • To form self-assembled monolayers (SAMs) of 4-aminothiophenol in the development of DNA biosensor. • As a linker to thiol (SH) functionalize multiwalled carbon nanotubes (MWCNTs). • To generate amino terminated self-assembly monolayers(SAMs) on platinum electrode which forms the base for attachment of single-wall carbon nano tubes (SWCTs). |
| General description: | 4-Aminothiophenol is a bifunctional aromatic thiol used to form self-assembled monolayers for biosensors. 4-Aminothiophenol (p-aminothiophenol, PATP) is an aromatic thiol. The self-assembly of silver and gold nano particles which are interconnected with 4-ATP to form metal-molecule-metal sandwich architecture has been characterized by surface enhanced Raman scattering (SERS) using an off-surface plasmon resonance condition. Chemical transformation of PATP to 4,4-dimercaptoazobenzene (DMAB) has been extensively studied. |
| Packaging: | 5, 25 g in glass bottle |
| Symbol |  GHS05 |
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | C |
| Risk Statements | 34 |
| Safety Statements | 26-28-36/37/39-45 |
| RIDADR | UN 3263 8 / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 235.4 °F - closed cup |
| Flash Point(C) | 113 °C - closed cup |
| Purity | ≥97.0% |
| bp | 140-145 °C/16 mmHg (lit.) |
| mp | 37-42 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352100 |