1-Ethylpiperidine hypophosphite
ALDRICH/436178 - 95%
Synonym: 1-Ethylpiperidinium phosphinate
CAS Number: 145060-63-5
Empirical Formula (Hill Notation): C7H18NO2P
Molecular Weight: 179.20
MDL Number: MFCD00216621
Linear Formula: C7H18NO2P
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 436178-25G
| assay | 95% |
| form | solid |
| InChI | 1S/C7H15N.H3O2P/c1-2-8-6- |
| InChI key | BNCZSWZTYPTERM-UHFFFAOYSA |
| mp | 40-43 °C (lit.) |
| SMILES string | OPO.CCN1CCCCC1 |
| storage temp. | 2-8°C |
| Application: | 1-Ethylpiperidine hypophosphite (EPHP) may be used in the following studies: • As water-soluble chain carrier for the efficient radical cyclization in water for various hydrophobic substrates. • In the main radical-cyclisation step for the synthesis of the phytotoxic metabolite alboatrin and its epimer. • Preparation of bifunctional pentafluorophenyl/2,4,6-t • Chemoselective radical reduction of the iodine atom in 1-deoxy-1-halo-1-iodo-ald |
| Application: | Reagent for: Synthesis of spiroketals via intramolecular iodoetherification A facile radical cyclization diverted to a rearrangement-cyclization with base Radical deoxygenation Synthesis of allylic H-phosphinates |
| General description: | 1-Ethylpiperidine hypophosphite promotes the carbon-carbon bond forming radical reactions in both aqueous and organic media. EPHP plays an important role of a good chain carrier during the radical addition of gem-dihalocompounds to electron-deficient olefins. It has been reported as a suitable radical reducing agent for organic halides. |
| Packaging: | 25 g in glass bottle |
| Symbol |   GHS02,GHS07 |
| Signal word | Warning |
| Hazard statements | H228 - H302 + H312 + H332 - H315 - H319 - H335 |
| Precautionary statements | P210 - P280 - P301 + P312 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338 |
| Hazard Codes | Xn |
| Risk Statements | 20/21/22-36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | UN1325 - class 4.1 - PG 2 - Flammable solids, organic, n.o.s., H |
| WGK Germany | WGK 3 |
| Flash Point(F) | 132.8 °F - closed cup |
| Flash Point(C) | 56 °C - closed cup |
| Purity | 95% |
| mp | 40-43 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352100 |