4-(Trifluoromethyl)phenylboronic acid
ALDRICH/439320 - ≥95.0%
Synonym: α,α,α-Trifluoro-p-tolylboronic acid; 4-
CAS Number: 128796-39-4
Empirical Formula (Hill Notation): C7H6BF3O2
Molecular Weight: 189.93
MDL Number: MFCD00151855
Linear Formula: CF3C6H4B(OH)2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 439320-1G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 439320-5G
| assay | ≥95.0% |
| InChI | 1S/C7H6BF3O2/c9-7(10,11)5 |
| InChI key | ALMFIOZYDASRRC-UHFFFAOYSA |
| mp | 245-250 °C (lit.) |
| SMILES string | OB(O)c1ccc(cc1)C(F)(F)F |
| Application: | 4-(Trifluoromethyl)phenyl • Site-selective Suzuki-Miyaura cross-coupling reactions. • Palladium-catalyzed direct arylation reactions. • Tandem-type Pd(II)-catalyzed oxidative Heck reaction and intramolecular C-H amidation sequence. • Ruthenium catalyzed direct arylation. • Ligand-free copper-catalyzed coupling reactions. • Amination and conjugate addition reactions. • Regioselective arylation and alkynylation by Suzuki-Miyaura and Sonogashira cross-coupling reactions. • Rhodium-catalyzed asymmetric 1,4-addition reactions. • Copper-catalyzed nitration reactions. • Regioselective Suzuki-Miyaura coupling and tandem palladium-catalyzed intramolecular aminocarbonylation and annulation. • Palladium catalyzed allylation reaction with allyl alcohols. • N-Arylation of imidazoles and amines in the presence of copper-exchanged fluorapatite as a catalyst. It can also be used as a reactant to prepare: • Thiazole derivatives for printable electronics. • Terphenyl benzimidazoles as tubulin polymerization inhibitors. • Aryl ketones by cross-coupling reaction with acid chlorides. |
| Other Notes: | Contains varying amounts of anhydride |
| Packaging: | 1, 5 g in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H302 |
| Hazard Codes | Xn |
| Risk Statements | 22 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95.0% |
| mp | 245-250 °C (lit.) |
| UNSPSC | 12352103 |