(1S,2R)-(−)-cis-1-Amino-2-indanol
ALDRICH/440833 - 99%
Synonym: (1S,2R)-(−)-cis-1-Amino-2-hydroxyindane
CAS Number: 126456-43-7
Empirical Formula (Hill Notation): C9H11NO
Molecular Weight: 149.19
MDL Number: MFCD00216655
Linear Formula: C9H11NO
Product Type: Chemical
| assay | 99% |
| form | powder |
| functional group | hydroxyl |
| InChI | 1S/C9H11NO/c10-9-7-4-2-1- |
| InChI key | LOPKSXMQWBYUOI-BDAKNGLRSA |
| mp | 118-121 °C (lit.) |
| optical purity | ee: 99% (GLC) |
| Quality Level | 100  |
| SMILES string | N[C@@H]1[C@H](O)Cc2ccccc1 |
| Application: | 1S,2R)-(-)-cis-1-Amino-2-indanol may be used to prepare: • (-)-1,2,5,6-Tetrahydrop • Oxazaborolidine catalysts, which can catalyze the asymmetric reduction of aromatic ketones with high enantioselectivity. • (RS,1S,2R)-(-)-2,4,6-Trimethylbenz |
| Application: | Used to prepare a mannitol-based scaffold in the study of Plasmepsin II inhibition. Aspartic proteases such as plasmepsins I and II are of interest as targets for new, potential anti-malarials. |
| General description: | (1S,2R)-(-)-cis-1-Amino-2-indanol is a main constituent of indinavir, a potent HIV (human immunodeficiency virus) protease inhibitor. |
| General description: | Useful chiral ligand for asymmetric synthesis. |
| Legal Information: | Sold under license from Sterling Pharma Solutions Limited. |
| Packaging: | 1, 5, 25 g in glass bottle |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26-36 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 99% |
| mp | 118-121 °C (lit.) |
| UNSPSC | 12352116 |