Methylenebis(phosphonic dichloride)
ALDRICH/447714 - 97%
CAS Number: 1499-29-2
Empirical Formula (Hill Notation): CH2Cl4O2P2
Molecular Weight: 249.78
MDL Number: MFCD00013901
Linear Formula: CH2[P(O)Cl2]2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 447714-5G
| assay | 97% |
| form | solid |
| InChI | 1S/CH2Cl4O2P2/c2-8(3,6)1- |
| InChI key | VRXYCDTWIOCJBH-UHFFFAOYSA |
| mp | 102-104 °C (lit.) |
| SMILES string | ClP(Cl)(=O)CP(Cl)(Cl)=O |
| Application: | Methylenebis(phosphonic dichloride) may be used for the following studies: • Synthesis of mycophenolic methylenebis(phosphonate) derivatives. • Phosphonylation of nucleosides. • Preparation of P,P′-partial esters of methylenebisphosphonic acid. • Synthesis of symmetrical di- and tetra- esters of methylenebisphosphonic acid. |
| General description: | Methylenebis(phosphonic dichloride) is an organophosphorus compound that is commonly used in phosphonylation reactions. It is more reactive and the rate of reaction is faster compared to POCl3. This is because the phosphorus center is more electrophilic due to the lack of electron back-donation from the CH2 group. |
| Packaging: | 5 g in glass bottle |
| Symbol |  GHS05 |
| Signal word | Danger |
| Hazard statements | H314 |
| Precautionary statements | P260 - P280 - P301 + P330 + P331 - P303 + P361 + P353 - P304 + P340 + P310 - P305 + P351 + P338 |
| Hazard Codes | C |
| Risk Statements | 14-34 |
| Safety Statements | 26-27-36/37/39-45 |
| RIDADR | UN 3261 8 / PGI |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Supplemental Hazard Statements | EUH014 |
| Purity | 97% |
| mp | 102-104 °C (lit.) |
| UNSPSC | 12352100 |