Fmoc-Gly-OH
ALDRICH/47627 - ≥98.0% (T)
Synonym: Fmoc-glycine
CAS Number: 29022-11-5
Empirical Formula (Hill Notation): C17H15NO4
Molecular Weight: 297.31
EC Number: 249-373-3
MDL Number: MFCD00037140
Linear Formula: C17H15NO4
Product Type: Chemical
| application(s) | peptide synthesis |
| assay | ≥98.0% (T) |
| form | powder |
| functional group | Fmoc |
| InChI | 1S/C17H15NO4/c19-16(20)9- |
| InChI key | NDKDFTQNXLHCGO-UHFFFAOYSA |
| mp | 174-175 °C (lit.) |
| 174-178 °C | |
| reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| SMILES string | OC(=O)CNC(=O)OCC1c2ccccc2 |
| storage temp. | 2-8°C |
| Application: | • Efficient Fmoc-Protected Amino Ester Hydrolysis Using Green Calcium (II) Iodide as a Protective Agent: This study describes the utilization of environmentally friendly calcium iodide in the hydrolysis of Fmoc-protected amino esters, enhancing reaction efficiency and sustainability (R Binette, M Desgagné, C Theaud, PL Boudreault - Molecules, 2022). Link to the article   .• α/β-Chimera peptide synthesis with cyclic β-sugar amino acids: the efficient coupling protocol: This research provides an advanced synthesis method for α/β-chimera peptides using cyclic β-sugar amino acids, demonstrating significant implications for peptide design in medicinal chemistry (A Nagy, V Goldschmidt Gőz, I Pintér, V Farkas - Amino acids, 2019). Link to the article .• MS, CD, and FT-IR characterization of five newly synthesized histidine-containing Ala-and Gly-based peptides: This paper presents detailed characterization of novel histidine-containing peptides, highlighting techniques that could be pivotal for peptide-based drug discovery (M Murariu, L Ion, CI Ciobanu, BA Petre - Rev. Roum Chem., 2017). Link to the article .• Efficient method for the concentration determination of fmoc groups incorporated in the core-shell materials by Fmoc–glycine: This article elaborates on an efficient method for determining the concentration of fmoc groups in core-shell materials, critical for the design of advanced functional materials (E Szczepańska, B Grobelna, J Ryl, A Kulpa - Molecules, 2020). Link to the article .• Circular aqueous fmoc/t‐bu solid‐phase peptide synthesis: This study explores a novel approach in solid-phase peptide synthesis, utilizing circular aqueous techniques that may offer greener and more efficient methodologies for peptide synthesis (J Pawlas, JH Rasmussen - ChemSusChem, 2021). Link to the article . |
| Other Notes: | Fmoc-glycine coupling of saccharide β-glycosylamines for the fractionation of oligosaccharides and formation of neoglycoconjugates. |
| Packaging: | 5, 50 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥98.0% (T) |
| mp | 174-175 °C (lit.); 174-178 °C |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352209 |