Fmoc-Leu-OH
ALDRICH/47633 - ≥97.0%
Synonym: N-
CAS Number: 35661-60-0
Empirical Formula (Hill Notation): C21H23NO4
Molecular Weight: 353.41
EC Number: 252-662-7
MDL Number: MFCD00037133
Linear Formula: C21H23NO4
Product Type: Chemical
| application(s) | peptide synthesis |
| assay | ≥97.0% |
| functional group | amine |
| carboxylic acid | |
| Fmoc | |
| InChI | 1S/C21H23NO4/c1-13(2)11-1 |
| InChI key | CBPJQFCAFFNICX-IBGZPJMESA |
| mp | 152-156 °C |
| 152-156 °C (lit.) | |
| optical activity | [α]20/D −25±2°, c = 1% in DMF |
| Quality Level | 100  |
| reaction suitability | reaction type: C-H Activation |
| reaction type: Fmoc solid-phase peptide synthesis | |
| reagent type: ligand reaction type: Peptide Synthesis |
|
| SMILES string | CC(C)C[C@H](NC(=O)OCC1c2c |
| storage temp. | 2-8°C |
| Application: | Fmoc-Leu-OH can be used as a reactant to synthesize: • Various oligopeptides by reacting with functionalized α-amino acid hydrochloride salts. • A cyclic depsipeptide sansalvamide A, a natural product found in marine fungus. • Streptocidin A−D, decapeptide antibiotics naturally found in Streptomyces sp. Tü 6071. • Coumaroyl dipeptide amide that can be used for cosmetic applications. |
| Biochem/physiol Actions: | PPARγ ligand that induces insulin sensitization, but not adipogenesis. |
| Packaging: | 5, 50 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥97.0% |
| mp | 152-156 °C (lit.); 152-156 °C |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352209 |