Fmoc-Cys(Trt)-OH
ALDRICH/47695 - ≥95.0% (sum of enantiomers, HPLC)
Synonym: N-
CAS Number: 103213-32-7
Empirical Formula (Hill Notation): C37H31NO4S
Molecular Weight: 585.71
MDL Number: MFCD00038538
Linear Formula: C37H31NO4S
Product Type: Chemical
| application(s) | peptide synthesis |
| assay | ≥95.0% (sum of enantiomers, HPLC) |
| functional group | Fmoc |
| InChI | 1S/C37H31NO4S/c39-35(40)3 |
| InChI key | KLBPUVPNPAJWHZ-UMSFTDKQSA |
| mp | 170-173 °C (lit.) |
| optical activity | [α]20/D +16.0±2°, c = 1% in THF |
| reaction suitability | reaction type: Fmoc solid-phase peptide synthesis |
| SMILES string | OC(=O)[C@H](CSC(c1ccccc1) |
| storage temp. | 2-8°C |
| Application: | Fmoc-Cys(Trt)-OH is an N-terminal protected cysteine derivative used in peptide synthesis. Some of the examples are: • Synthesis of mono- and bi-functionalized platinum(IV) complexes to target angiogenic tumor vasculature. • Synthesis of proteins through native chemical ligation of peptide hydrazides as thioester surrogates via solid-phase synthesis. • Synthesis of glycoconjugates by conjugating reducing sugars to cysteine residues of peptides. |
| General description: | Fmoc-Cys(Trt)-OH is an amino acid commonly used in the Fmoc solid-phase peptide synthesis. |
| Packaging: | 5 g in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥95.0% (sum of enantiomers, HPLC) |
| mp | 170-173 °C (lit.) |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352209 |