cis-Diamineplatinum(II) dichloride
ALDRICH/479306 - ≥99.9% trace metals basis
Synonym: cis-Diammineplatinum(II) dichloride; cis-Dichlorodiammine platinum(II); cis-Platinum(II) diammine dichloride; Cisplatin
CAS Number: 15663-27-1
Empirical Formula (Hill Notation): H6Cl2N2Pt
Molecular Weight: 300.05
EC Number: 239-733-8
MDL Number: MFCD00011623
Linear Formula: Pt(NH3)2Cl2
Product Type: Chemical
antibiotic activity spectrum | neoplastics |
assay | ≥99.9% trace metals basis |
InChI | 1S/2ClH.2H3N.Pt/h2*1H;2*1 |
InChI key | LXZZYRPGZAFOLE-UHFFFAOYSA |
mode of action | DNA synthesis | interferes |
mp | 270 °C (lit.) |
Quality Level | 100 |
reaction suitability | core: platinum |
reagent type: catalyst | |
SMILES string | N.N.Cl[Pt]Cl |
Application: | cis-Diamineplatinum(II) dichloride can be used as a model drug to test the efficiency of various drug carriers in drug delivery. |
Application: | Highly active chemotherapeutic agent for use in preventing the advancement of testicular cancer. |
Biochem/physiol Actions: | Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links. |
Packaging: | 1, 5, 50 g in glass bottle |
Symbol | GHS06,GHS08 |
Signal word | Danger |
Hazard statements | H300 - H315 - H317 - H319 - H334 - H335 - H350 |
Precautionary statements | P201 - P261 - P280 - P301 + P310 + P330 - P304 + P340 + P312 - P308 + P313 |
Hazard Codes | T |
Risk Statements | 45-25-41 |
Safety Statements | 53-26-39-45 |
RIDADR | UN 3288 6.1 / PGII |
WGK Germany | WGK 3 |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Purity | ≥99.9% trace metals basis |
mp | 270 °C (lit.) |
UNSPSC | 12161600 |