cis-Diamineplatinum(II) dichloride
ALDRICH/479306 - ≥99.9% trace metals basis
Synonym: cis-Diammineplatinum(II) dichloride; cis-Dichlorodiammine platinum(II); cis-Platinum(II) diammine dichloride; Cisplatin
CAS Number: 15663-27-1
Empirical Formula (Hill Notation): H6Cl2N2Pt
Molecular Weight: 300.05
EC Number: 239-733-8
MDL Number: MFCD00011623
Linear Formula: Pt(NH3)2Cl2
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 479306-50G
| antibiotic activity spectrum | neoplastics |
| assay | ≥99.9% trace metals basis |
| InChI | 1S/2ClH.2H3N.Pt/h2*1H;2*1 |
| InChI key | LXZZYRPGZAFOLE-UHFFFAOYSA |
| mode of action | DNA synthesis | interferes |
| mp | 270 °C (lit.) |
| Quality Level | 100  |
| reaction suitability | core: platinum |
| reagent type: catalyst | |
| SMILES string | N.N.Cl[Pt]Cl |
| Application: | cis-Diamineplatinum(II) dichloride can be used as a model drug to test the efficiency of various drug carriers in drug delivery. |
| Application: | Highly active chemotherapeutic agent for use in preventing the advancement of testicular cancer. |
| Biochem/physiol Actions: | Potent platinum-based antineoplastic agent. Forms cytotoxic adducts with the DNA dinucleotide d(pGpG), inducing intrastrand cross-links. |
| Packaging: | 1, 5, 50 g in glass bottle |
| Symbol |   GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H300 - H315 - H317 - H319 - H334 - H335 - H350 |
| Precautionary statements | P201 - P261 - P280 - P301 + P310 + P330 - P304 + P340 + P312 - P308 + P313 |
| Hazard Codes | T |
| Risk Statements | 45-25-41 |
| Safety Statements | 53-26-39-45 |
| RIDADR | UN 3288 6.1 / PGII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99.9% trace metals basis |
| mp | 270 °C (lit.) |
| UNSPSC | 12161600 |