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O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine

ALDRICH/480894 - 96%

CAS Number: 6723-30-4
Empirical Formula (Hill Notation): C5H11NO2
Molecular Weight: 117.15
MDL Number: MFCD01321374
Linear Formula: C5H11NO2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-480894-1G 1 g
 $115.00
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This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 480894-1G

 

assay 96%
bp 81 °C/20 mmHg (lit.)
InChI 1S/C5H11NO2/c6-8-5-3-1-2-4-7-5/h5H,1-4,6H2
InChI key NLXXVSKHVGDQAT-UHFFFAOYSA-N
mp 34-37 °C (lit.)
SMILES string NOC1CCCCO1
Application: O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine may be used in the synthesis of 2-(5-bromothiophene-2-sulfonamido)-N-(tetrahydro-2H-pyran-2-yloxy)acetamides.
It may be used in the synthesis of the following potential histone deacetylase (HDAC) inhibitors:
• 2-[1-(naphthalene-2-sulfonyl)-heterocyclyl]-pyrimidine-5-carboxylic acid (tetrahydropyran-2-yloxy)-amides
• (E)-3-(2-benzyl-1-oxoisoindolin-6-yl)-N-(tetrahydro-2H-pyran-2-yloxy)acrylamide
• 3-(1-benzenesulfonyl-2,3-dihydro-1H-indol-5-yl)-N-hydroxy-acrylamide
General description: O-(Tetrahydro-2H-pyran-2-yl)hydroxylamine (OTX) is an O-substituted hydroxylamine. The coupling of OTX with alkaline gel electrophoresis has been reported to improve the process of detecting single strand breaks (SSBs) in DNA.
Packaging: 1 g in glass bottle
Purity 96%
bp 81 °C/20 mmHg (lit.)
mp 34-37 °C (lit.)
UNSPSC 12352100

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