L-Glutamic acid γ-benzyl ester

ALDRICH/49510 - ≥99.0% (T)

Synonym: L-Glutamic acid 5-benzyl ester

CAS Number: 1676-73-9
Empirical Formula (Hill Notation): C₁₂H₁₅NO₄
Molecular Weight: 237.25
EC Number: 216-826-1
MDL Number: MFCD00002633
Linear Formula: C₆H₅CH₂OCOCH₂CH₂CH(NH₂)COOH
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-49510-5G	5 g	$46.30 1/EA	Add To Favorites
45-49510-25G	25 g	$120.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

application(s)	peptide synthesis
assay	≥99.0% (T)
InChI	1S/C12H15NO4/c13-10(12(15)16)6-7-11(14)17-8-9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,15,16)/t10-/m0/s1
InChI key	BGGHCRNCRWQABU-JTQLQIEISA-N
mp	181-182 °C (lit.)
optical activity	[α]20/D +19±2°, c = 1% in acetic acid
Quality Level	100
reaction suitability	reaction type: solution phase peptide synthesis
SMILES string	N[C@@H](CCC(=O)OCc1ccccc1)C(O)=O
storage temp.	2-8°C

Application:

L-Glutamic acid γ-benzyl ester is commonly used in the synthesis of polymers for biological applications. Some of the examples are:
• Synthesis of bioreducible block copolymers based on poly(ethylene glycol) and poly(γ-benzyl L-glutamate) for Intracellular drug delivery.
• Synthesis of biodegradable poly(L-glutamic acid)-b-polylactide for magnetic resonance imaging (MRI)-visible drug delivery system.
• Synthesis of pH and temperature-responsive diblock copolymers based on poly(L-glutamic acid).

Packaging:

5, 25 g in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	≥99.0% (T)
mp	181-182 °C (lit.)
Storage Temp.	2-8°C
UNSPSC	12352209

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