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L-Glutamic acid γ-benzyl ester

ALDRICH/49510 - ≥99.0% (T)

Synonym: L-Glutamic acid 5-benzyl ester

CAS Number: 1676-73-9
Empirical Formula (Hill Notation): C12H15NO4
Molecular Weight: 237.25
EC Number: 216-826-1
MDL Number: MFCD00002633
Linear Formula: C6H5CH2OCOCH2CH2CH(NH2)COOH
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-49510-5G 5 g
$42.10
1/EA
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45-49510-25G 25 g
$109.00
1/EA
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application(s) peptide synthesis
assay ≥99.0% (T)
InChI 1S/C12H15NO4/c13-10(12(15)16)6-7-11(14)17-8-9-4-2-1-3-5-9/h1-5,10H,6-8,13H2,(H,15,16)/t10-/m0/s1
InChI key BGGHCRNCRWQABU-JTQLQIEISA-N
mp 181-182 °C (lit.)
optical activity [α]20/D +19±2°, c = 1% in acetic acid
Quality Level 100 
reaction suitability reaction type: solution phase peptide synthesis
SMILES string N[C@@H](CCC(=O)OCc1ccccc1)C(O)=O
storage temp. 2-8°C
Application: L-Glutamic acid γ-benzyl ester is commonly used in the synthesis of polymers for biological applications. Some of the examples are:
• Synthesis of bioreducible block copolymers based on poly(ethylene glycol) and poly(γ-benzyl L-glutamate) for Intracellular drug delivery.
• Synthesis of biodegradable poly(L-glutamic acid)-b-polylactide for magnetic resonance imaging (MRI)-visible drug delivery system.
• Synthesis of pH and temperature-responsive diblock copolymers based on poly(L-glutamic acid).

Packaging: 5, 25 g in glass bottle
RIDADR NONH for all modes of transport
WGK Germany WGK 3
Flash Point(F) Not applicable
Flash Point(C) Not applicable
Purity ≥99.0% (T)
mp 181-182 °C (lit.)
Storage Temp. 2-8°C
UNSPSC 12352209

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