PAMAM-OH dendrimer, generation 6 solution
ALDRICH/536822 - 5 wt. % in methanol
Empirical Formula (Hill Notation): C2542H4832N762O764
Molecular Weight: 58298.21
MDL Number: MFCD00197936
Linear Formula: [NH2(CH2)2NH2]:(G=6);dendri PAMAM(NHCH2CH2OH)256
Product Type: Chemical
| concentration | 5 wt. % in methanol |
| density | 0.807 g/mL at 25 °C |
| description | amidoethanol surface groups |
| feature | core type ethylenediamine core (2-carbon core) |
| form | liquid |
| mol wt | generation 6 |
| no. Surface Groups | 256 |
| Quality Level | 100  |
| refractive index | n |
| storage temp. | 2-8°C |
| Application: | PAMAM-OH dendrimer can be used to formulate poorly water-soluble drugs to increase water solubility, and therefore enhance the bioavailability of these drugs. It can also be applied to catalysts and organic molecules, where dendrimers function as solubility enhancers and modifiers. |
| General description: | PAMAM-OH (poly(amidoamine) dendrimers are highly branched core-shell nanostructures with surface hydroxyl groups. The presence of hydroxyl groups on the surface of the PAMAM-OH dendrimer molecule leads to stronger interaction with the components of the cell membrane via the formation of hydrogen bonds. This type of interaction can modify the properties and function of cell membranes. PAMAM-OH dendrimers also have an advantage over PAMAM dendrimers in terms of cytotoxicity and aggregation problems because of the absence of amine functionality. |
| Legal Information: | Dendritech is a registered trademark of Dendritech, Inc. |
| Legal Information: | Manufactured by Dendritech®, Inc. |
| Packaging: | 5 g in glass bottle |
| Physical form: | Contains 256 surface hydroxyl groups. |
| Symbol |    GHS02,GHS06,GHS08 |
| Signal word | Danger |
| Hazard statements | H225 - H301 + H311 + H331 - H370 |
| Precautionary statements | P210 - P280 - P301 + P310 + P330 - P302 + P352 + P312 - P304 + P340 + P311 |
| Hazard Codes | F,T |
| Risk Statements | 11-23/24/25-39/23/24/25 |
| Safety Statements | 16-36/37-45 |
| RIDADR | UN1230 - class 3 - PG 2 - Methanol, solution |
| WGK Germany | WGK 3 |
| Flash Point(F) | 51.8 °F - closed cup |
| Flash Point(C) | 11 °C - closed cup |
| Density | 0.807 g/mL at 25 °C |
| Refractive Index | n |
| Storage Temp. | 2-8°C |
| UNSPSC | 12162002 |