6-Maleimidohexanoic acid N-hydroxysuccinimide ester

ALDRICH/568600 - 98%

Synonym: 6-Maleimidocaproic acid N-succinimidyl ester; N-(ε-Maleimidocaproyloxy)succinimide; N-Succinimidyl 6-maleimidocaproate; EMCS

CAS Number: 55750-63-5
Empirical Formula (Hill Notation): C₁₄H₁₆N₂O₆
Molecular Weight: 308.29
MDL Number: MFCD00043043
Linear Formula: C₁₄H₁₆N₂O₆
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-568600-500MG	500 mg	$669.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

assay	98%
functional group	imide
	maleimide
	NHS ester
InChI	1S/C14H16N2O6/c17-10-5-6-11(18)15(10)9-3-1-2-4-14(21)22-16-12(19)7-8-13(16)20/h5-6H,1-4,7-9H2
InChI key	VLARLSIGSPVYHX-UHFFFAOYSA-N
mp	70-73 °C (lit.)
Quality Level	100
reaction suitability	reagent type: cross-linking reagent
SMILES string	O=C(ON(C(CC1)=O)C1=O)CCCCCN2C(C=CC2=O)=O
storage temp.	−20°C

Application:

6-Maleimidohexanoic acid N-hydroxysuccinimide ester can be used in:
• Synthesis of maleimide-activated carbohydrates for site-specific glycosylation of cysteine-containing peptides and proteins via maleimide-thiol ligation reaction.
• Synthesis of a glucuronide prodrug of doxorubicin bearing a maleimide side chain as an antitumor agent.
• Cross-linking oligonucleotides with the amino groups on the substrate to fabricate DNA microarrays.

Packaging:

500 mg in amber glass bottle

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26-36
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	98%
mp	70-73 °C (lit.)
Storage Temp.	−20°C
UNSPSC	12352100

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