Hoveyda-Grubbs Catalyst^® M720

ALDRICH/569755 - Umicore, 97%

Synonym: Hoveyda-Grubbs Catalyst^® 2nd Generation; Hoveyda-Grubbs Catalyst^® M72 (C627); (1,3-Bis-(2,4,6-trimethylphenyl)-2-imidazolidinylidene)dichloro(o-isopropoxyphenylmethylene)ruthenium; Dichloro[1,3-bis(2,4,6-trimethylphenyl)-2-imidazolidinylidene](2-isopropoxyphenylmethylene)ruthenium(II); Grubbs Catalyst^® C627

CAS Number: 301224-40-8
Empirical Formula (Hill Notation): C₃₁H₃₈Cl₂N₂ORu
Molecular Weight: 626.62
MDL Number: MFCD03701614
Linear Formula: C₃₁H₃₈Cl₂N₂ORu
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-569755-100MG	100 mg	DISCONTINUED
45-569755-500MG	500 mg	DISCONTINUED
45-569755-2G	2 g	DISCONTINUED
45-569755-10G	10 g	DISCONTINUED
45-569755-25G	25 g	DISCONTINUED

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 569755-10G

Properties
Descriptions
Safety Info.
Basic Data

assay	97%
form	solid
InChI	1S/C21H26N2.C10H12O.2ClH.Ru/c1-14-9-16(3)20(17(4)10-14)22-7-8-23(13-22)21-18(5)11-15(2)12-19(21)6;1-8(2)11-10-7-5-4-6-9(10)3;;;/h9-12H,7-8H2,1-6H3;3-8H,1-2H3;2*1H;/q;;;;+2/p-2
InChI key	ZRPFJAPZDXQHSM-UHFFFAOYSA-L
mp	216-220 °C (lit.)
Quality Level	100
reaction suitability	core: ruthenium
	reagent type: catalyst reaction type: Ring-Opening Polymerization
SMILES string	CC(C)Oc1ccccc1C=[Ru](Cl)(Cl)=C2N(CCN2c3c(C)cc(C)cc3C)c4c(C)cc(C)cc4C
storage temp.	2-8°C

Application:	It′s a phosphine free version of Grubbs 2^nd Generation Catalyst with comparable reactivity, but initiates more readily at lower temperatures. Efficient for metathesis of electron-deficient substrates including fluorinated olefins. Demonstrated in multiple large-scale pharmaceutical applications. It can be used as a catalyst for olefin cross-metathesis with fluorinated olefins (CM), ring-closing metathesis (RCM), ring-opening metathesis (ROM), and a sequence of a metathesis reaction and subsequent dihydroxylation of the newly formed double bond. Learn more about our metathesis catalysts
Legal Information:	Grubbs Catalyst is a registered trademark of Umicore AG & Co. KG
Legal Information:	Product of Umicore Product License This product, its manufacturing or use, is the subject of one or more issued or pending U.S. Patents (and foreign equivalents) owned or controlled by Umicore PMC. The purchase of this product from Umicore PMC through Sigma-Aldrich, its affiliates or their authorized distributors conveys to the buyer a limited, one-time, non-exclusive, non-transferable, non-assignable license. Buyer’s use of this product may infringe patents owned or controlled by third parties. It is the sole responsibility of buyer to ensure that its use of the product does not infringe the patent rights of third parties or exceed the scope of the license granted herein. For any further information on product please refer to your local Umicore PMC contact at http://www.pmc.umicore.com
Other Notes:	Grubbs Catalyst^® Technology for Olefin Metathesis by Aldrich
Packaging:	100, 500 mg in glass bottle
Packaging:	2, 10, 25 g in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	97%
mp	216-220 °C (lit.)
Storage Temp.	2-8°C
UNSPSC	12161600

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