CyJohnPhos

ALDRICH/638099 - 97%

Synonym: 2-(Dicyclohexylphosphino)biphenyl; (2-Biphenyl)dicyclohexylphosphine; Cyclohexyl JohnPhos

CAS Number: 247940-06-3
Empirical Formula (Hill Notation): C₂₄H₃₁P
Molecular Weight: 350.48
MDL Number: MFCD01862441
Linear Formula: C₂₄H₃₁P
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-638099-1G	1 g	$43.30 1/EA	Add To Favorites
45-638099-5G	5 g	$129.00 1/EA	Add To Favorites
45-638099-25G	25 g	$501.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

assay	97%
functional group	phosphine
InChI	1S/C24H31P/c1-4-12-20(13-5-1)23-18-10-11-19-24(23)25(21-14-6-2-7-15-21)22-16-8-3-9-17-22/h1,4-5,10-13,18-19,21-22H,2-3,6-9,14-17H2
InChI key	LCSNDSFWVKMJCT-UHFFFAOYSA-N
mp	102-106 °C (lit.)
Quality Level	100
reaction suitability	reaction type: Cross Couplings
	reagent type: ligand reaction type: Arylations
	reagent type: ligand reaction type: Buchwald-Hartwig Cross Coupling Reaction
	reagent type: ligand reaction type: C-X Bond Formation
	reagent type: ligand reaction type: Hiyama Coupling
	reagent type: ligand reaction type: Methylations
	reagent type: ligand reaction type: Negishi Coupling
	reagent type: ligand reaction type: Oxidations
	reagent type: ligand reaction type: Suzuki-Miyaura Coupling
SMILES string	C1CCC(CC1)P(C2CCCCC2)c3ccccc3-c4ccccc4

Application:	CyJohnPhos may be used in combination with a nickel catalyst for the Suzuki-Miyaura arylation of tertiary benzylic acetates with aryl boroxines to produce diaryl and triaryl quaternary stereocenters.
Application:	Ligand employed in the palladium-catalysed synthesis of 1,3,5-tris(2′-aminophenyl)benzene, a core building block for potential ionic receptors.
Application:	Ligand for amination of aryl halides and triflates.
General description:	CyJohnPhos [(2-Biphenyl)dicyclohexylphosphine] is an air-stable, bulky and electron-rich monodentate biarylphosphine ligand developed by the Buchwald group to enhance the reactivity of palladium catalysis during cross-coupling reactions. Learn more about Buchwald Phosphine Ligands
Legal Information:	Usage subject to US Patents 6307087 and 6395916.
Packaging:	1, 5, 25, 100 g in glass bottle

Hazard statements	H413
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	97%
mp	102-106 °C (lit.)
UNSPSC	12352002

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