(1R,1′R,2S,2′S)-DuanPhos
ALDRICH/657697
Synonym: (1R,1′R,2S,2′S)-2,2′-Di-tert-butyl-2,3,2′,3′-tetrahydro-1H,1′H-(1,1′)biisophosphindolyl
CAS Number: 528814-26-8
Empirical Formula (Hill Notation): C24H32P2
Molecular Weight: 382.46
Linear Formula: C24H32P2
Product Type: Chemical
| InChI | 1S/C24H32P2/c1-23(2,3)25- |
| InChI key | HCBRTCFUVLYSKU-SAZLYLDSSA |
| mp | 214-246 °C |
| optical activity | [α]20/D +18°, c = 1 in chloroform |
| SMILES string | CC(C)(C)P1Cc2ccccc2C1C3P( |
| Application: | Chiral Quest Phosphine Ligands for Asymmetric Hydrogenation  Catalytic ligand used for: • Stereoselective synthesis of cyano-substituted dihydropyrroles by annulation of cyanoallenes • Rhodium-catalyzed intermolecular enantioselective hydroacylation of alkynes to give alpha- and beta-substituted unsaturated ketones by kinetic resolution • Stereoselective preparation of β-amino nitriles via rhodium-catalyzed asymmetric hydrogenation of amino acrylonitriles • Stereoselective preparation of anti-1,3-amino alcohols via rhodium-catalyzed asymmetric hydrogenation of β-ketoenamide intermediates • Stereoselective preparation of acetylaminoindane via rhodium-catalyzed asymmetric hydrogenation of acetylaminoindene |
| General description: | (1R,1′R,2S,2′S)-DuanPhos is an electron-rich chiral phosphine ligand mainly for transition metal catalyzed asymmetric hydrogenation. |
| Packaging: | 100, 500 mg in amber glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| mp | 214-246 °C |
| UNSPSC | 12352005 |