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(R)-(+)-3,3,3-Trifluoro-1,2-epoxypropane

ALDRICH/667005 - 97%

Synonym: (R)-(+)-2-(Trifluoromethyl)oxirane

CAS Number: 143142-90-9
Empirical Formula (Hill Notation): C3H3F3O
Molecular Weight: 112.05
MDL Number: MFCD08276876
Linear Formula: C3H3F3O
Product Type: Chemical

Catalog Number PKG Qty. Price Quantity
45-667005-1G 1 g
$426.00
1/EA
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assay 97%
bp 25-32 °C
density 1.294 g/mL at 25 °C
InChI 1S/C3H3F3O/c4-3(5,6)2-1-7-2/h2H,1H2/t2-/m1/s1
InChI key AQZRARFZZMGLHL-UWTATZPHSA-N
refractive index n20/D <1.300
SMILES string FC(F)(F)[C@H]1CO1
storage temp. 2-8°C
Application: (R)-(+)-3,3,3-Trifluoro-1,2-epoxypropane can be used as a substrate to synthesize:
•  Substituted trifluoro amino propanols, which are found to be potent inhibitors of cholesteryl ester transfer protein.
•  (2R) Trifluoro-(methoxybenzyloxy)-propanol (chiral glycol) by reacting with 4-methoxybenzyl alcohol in the presence of NaH. Chiral glycol intermediate is further utilized for the preparation of trifluoromethyl glycol carbamates as potential monoacylglycerol lipase (MAGL) inhibitors.

Packaging: 1 g in glass bottle
Packaging: 250 mg in glass bottle
Symbol GHS02  GHS02
Signal word Danger
Hazard statements H224
Precautionary statements P210 - P403 + P233
Hazard Codes F+
Risk Statements 12
Safety Statements 3
RIDADR UN 1993A 3 / PGI
WGK Germany WGK 3
Flash Point(F) -14.8 °F
Flash Point(C) -26 °C
Purity 97%
bp 25-32 °C
Density 1.294 g/mL at 25 °C
Refractive Index n20/D <1.300
Storage Temp. 2-8°C
UNSPSC 12352005

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