Synonym: α,α-Diphenyl-D-prolinolmethylboronic acid cyclamide ester; (R)-1-Methyl,3,3-diphenyl-tetrahydro-pyrrolo(1,2-c)(1,3,2)oxazaborole; (R)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole
CAS Number: 112022-83-0
Empirical Formula (Hill Notation): C18H20BNO
Molecular Weight: 277.17
MDL Number: MFCD00078440
Linear Formula: C18H20BNO
Product Type: Chemical
| concentration |
1 M in THF |
| density |
0.942 g/mL at 25 °C |
| InChI |
1S/C18H20BNO/c1-19-20-14-8-13-17(20)18(21-19,15-9-4-2-5-10-15)16-11-6-3-7-12-16/h2-7,9-12,17H,8,13-14H2,1H3/t17-/m1/s1 |
| InChI key |
VMKAFJQFKBASMU-QGZVFWFLSA-N |
| optical activity |
[α]22/D +76.8°, c = 1 in toluene |
| refractive index |
n20/D 1.4602 |
| SMILES string |
[H][C@]12CCCN1B(C)OC2(c3ccccc3)c4ccccc4 |
| Application: |
CBS Catalysts for Asymmetric Reduction and Asymmetric Synthesis   |
| Application: |
The CBS (Corey-Bakshi-Shibata) oxazaborolidine catalyst has been used in the asymmetric reduction of prochiral ketones. Other applications include the enantioselective synthesis of α-hydroxy acids, α-amino acids, C2 symmetrical ferrocenyl diols, and propargyl alcohols. |
| Packaging: |
5, 25 mL in glass bottle |
| Density |
0.942 g/mL at 25 °C |
| Refractive Index |
n20/D 1.4602 |
| UNSPSC |
12352005 |
GHS02,GHS07,GHS08