2-(Diphenylphosphino)terephthalic acid 1-methyl 4-pentafluorophenyl diester
ALDRICH/679011 - 97%
Synonym: 1-
CAS Number: 932710-65-1
Empirical Formula (Hill Notation): C27H16F5O4P
Molecular Weight: 530.38
MDL Number: MFCD09265125
Linear Formula: C27H16F5O4P
Product Type: Chemical
| assay | 97% |
| form | solid |
| InChI | 1S/C27H16F5O4P/c1-35-27(3 |
| InChI key | OURNVXDJALDDIG-UHFFFAOYSA |
| mp | 109-111 °C |
| reaction suitability | reaction type: click chemistry |
| SMILES string | COC(=O)c1ccc(cc1P(c2ccccc |
| storage temp. | −20°C |
| Application: | • Staudinger ligation reagent for the conjugation of amine and azide containing compounds or biomolecules. • The amine functionalized molecule first reacts with the phosphine through the activated pentafluorophenyl ester.The azide-molecule is then reacted with the newly labeled phosphine to form the iminophosphorane, and the aza-ylide is subsequently captured by the methyl ester to yield the covalent conjugated product.  The Staudinger Ligation: A High-Yield, Chemoselective, and Mild Synthetic Method  |
| Packaging: | 100 mg in clear glass bottle |
| Packaging: | 25 mg in amber glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 97% |
| mp | 109-111 °C |
| Storage Temp. | −20°C |
| UNSPSC | 12352106 |