4-Methoxybenzyl-2,2,2-trichloroacetimidate

ALDRICH/679585

Synonym: p-Methoxybenzyl trichloroacetimidate

CAS Number: 89238-99-3
Empirical Formula (Hill Notation): C₁₀H₁₀Cl₃NO₂
Molecular Weight: 282.55
MDL Number: MFCD00134547
Linear Formula: C₁₀H₁₀Cl₃NO₂
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-679585-5G	5 g	$174.00 1/EA	Add To Favorites
45-679585-25G	25 g	$398.00 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

bp	135-137 °C/0.7 mmHg
density	1.361 g/mL at 25 °C
functional group	chloro
	ether
impurities	Major impurity is Trichloroacetamide by GCMS.
InChI	1S/C10H10Cl3NO2/c1-15-8-4-2-7(3-5-8)6-16-9(14)10(11,12)13/h2-5,14H,6H2,1H3
InChI key	TYHGKLBJBHACOI-UHFFFAOYSA-N
Quality Level	100
refractive index	n20/D 1.5488
SMILES string	COc1ccc(COC(=N)C(Cl)(Cl)Cl)cc1
storage temp.	2-8°C

Application:

4-Methoxybenzyl-2,2,2-trichloroacetimidate can be used as a reagent for the protection of alcohols as the p-methoxybenzyl ether. 1^o, 2^o, and 3^o alcohols can be easily protected using this reagent with equal efficiency in the presence of a variety of different protective groups. This reagent is commonly used under acidic conditions therefore it offers an alternative method to the Williamson ether synthesis, which is typically used basic conditions to protect base-sensitive alcohols.

Packaging:

5, 25 g in glass bottle

Symbol	GHS07,GHS09
Signal word	Warning
Hazard statements	H302 + H312 + H332 - H315 - H319 - H335 - H411
Precautionary statements	P273 - P280 - P301 + P312 + P330 - P302 + P352 + P312 - P304 + P340 + P312 - P305 + P351 + P338
Hazard Codes	Xn,N
Risk Statements	20/21/22-36/37/38-51/53
Safety Statements	26-36/37-61
RIDADR	UN 3082 9 / PGIII
WGK Germany	WGK 3
Flash Point(F)	> 230.0 °F
Flash Point(C)	> 110 °C

bp	135-137 °C/0.7 mmHg
Density	1.361 g/mL at 25 °C
Refractive Index	n20/D 1.5488
Storage Temp.	2-8°C
UNSPSC	12352101

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