3,3-Difluoropyrrolidine hydrochloride
ALDRICH/694509 - 97%
CAS Number: 163457-23-6
Empirical Formula (Hill Notation): C4H7F2N · HCl
Molecular Weight: 143.56
MDL Number: MFCD03788948
Linear Formula: C4H7F2N · HCl
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 694509-250MG.
| assay | 97% |
| form | solid |
| functional group | fluoro |
| InChI | 1S/C4H7F2N.ClH/c5-4(6)1-2 |
| InChI key | YYVPZQADFREIFR-UHFFFAOYSA |
| mp | 133-136 °C |
| Quality Level | 100  |
| SMILES string | Cl.FC1(F)CCNC1 |
| Application: | 3,3-Difluoropyrrolidine hydrochloride can be used as a building block in the synthesis of: • Triazole substituted prolyl difluoropyrrolidines as potential inhibitors of dipeptidyl peptidase-4. • Dual leucine zipper kinase (DLK) inhibitors. It can be also used as a reactant in the preparation of cyclic and acyclic β-aminofluoroalkenes via allylic amination using the Pd catalyst. |
| Packaging: | 1 g in glass bottle |
| Packaging: | 250 mg in glass insert |
| Symbol |  GHS07 |
| Signal word | Warning |
| Hazard statements | H315 - H319 - H335 |
| Precautionary statements | P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 97% |
| mp | 133-136 °C |
| UNSPSC | 12352100 |