Bis(3,5-di(trifluoromethyl)phenyl)chlorophosphine

ALDRICH/694746

Synonym: P,P-Bis[3,5-bis(trifluoromethyl)phenyl]phosphinous chloride

CAS Number: 142421-57-6
Empirical Formula (Hill Notation): C₁₆H₆ClF₁₂P
Molecular Weight: 492.63
MDL Number: MFCD01630852
Linear Formula: C₁₆H₆ClF₁₂P
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-694746-500MG	500 mg	$82.40 1/EA	Add To Favorites

Properties
Descriptions
Safety Info.
Basic Data

form	solid
functional group	phosphine
InChI	1S/C16H6ClF12P/c17-30(11-3-7(13(18,19)20)1-8(4-11)14(21,22)23)12-5-9(15(24,25)26)2-10(6-12)16(27,28)29/h1-6H
InChI key	DFZQEHBNAJGDCT-UHFFFAOYSA-N
mp	25-29 °C
reaction suitability	reaction type: Buchwald-Hartwig Cross Coupling Reaction
	reaction type: Heck Reaction
	reaction type: Hiyama Coupling
	reaction type: Negishi Coupling
	reaction type: Sonogashira Coupling
	reaction type: Stille Coupling
	reaction type: Suzuki-Miyaura Coupling
	reagent type: ligand
SMILES string	FC(F)(F)c1cc(cc(c1)C(F)(F)F)P(Cl)c2cc(cc(c2)C(F)(F)F)C(F)(F)F

Application:

Reactant for synthesis of:
• Chiral phosphine-aminophosphine ligands for rhodium-catalyzed asymmetric hydrogenation
• Ligands for palladium-catalyzed stereoselective allylation reactions
• Ligands for enantioselective hydrogenations
• Josiphos analog as catalyst for asymmetric hydrogenation
• Ligands used in asymmetric hydrovinylation reactions

Reactant for enantioselective hydrogenation reactions catalyzed by Ru-(phosphine-oxazoline) complexes

Packaging:

100, 500 mg in glass bottle

Symbol	GHS02,GHS05
Signal word	Danger
Hazard statements	H261 - H314
Precautionary statements	P231 + P232 - P280 - P305 + P351 + P338 - P310 - P422
Hazard Codes	C
Risk Statements	14-34
Safety Statements	26-36/37/39-45
RIDADR	UN 3096 4.3(8) / PGII
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

mp	25-29 °C
UNSPSC	12352002

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