2-Morpholinoethyl isocyanide
ALDRICH/69893 - ≥98.0% (GC)
Synonym: 4-
CAS Number: 78375-48-1
Empirical Formula (Hill Notation): C7H12N2O
Molecular Weight: 140.18
MDL Number: MFCD00040506
Linear Formula: C7H12N2O
Product Type: Chemical
| assay | ≥98.0% (GC) |
| bp | 72-73 °C/0.7 mmHg (lit.) |
| density | 1.017 g/mL at 20 °C (lit.) |
| form | liquid |
| InChI | 1S/C7H12N2O/c1-8-2-3-9-4- |
| InChI key | MFRZPLYKVDHOSN-UHFFFAOYSA |
| Quality Level | 200  |
| refractive index | n |
| SMILES string | [C-]#[N+]CCN1CCOCC1 |
| storage temp. | −20°C |
| Application: | 2-Morpholinoethyl isocyanide can be used for the synthesis of: • Nitrogen acyclic carbene (NAC) complexes to be used as catalysts for the synthesis of phenol and hydration of alkynes. • Variety of imidazo[1,2-a]pyridines and α-acylaminoamides by Ugi condensation reaction. • 2-Aminobenzoxazoles and 3-aminobenzoxazines having important therapeutic activities. It can also be used as a ligand in bis-cyclometalated iridium complexes for the organic light emitting diodes (OLEDs). |
| Other Notes: | Potent coupling reagent for peptide synthesis giving higher yields and less racemization than DCCI; Reagent used in a Passerini-like reaction to alpha-hydroxy amides |
| Packaging: | 10, 50 mL in glass bottle |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 + H311 + H331 - H315 - H319 - H335 |
| Precautionary statements | P261 - P280 - P301 + P310 - P302 + P352 + P312 - P304 + P340 + P311 - P305 + P351 + P338 |
| Hazard Codes | T |
| Risk Statements | 23/24/25-36/37/38 |
| Safety Statements | 26-36/37-45 |
| RIDADR | UN 2810 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | 230.0 °F - closed cup |
| Flash Point(C) | 110 °C - closed cup |
| Purity | ≥98.0% (GC) |
| bp | 72-73 °C/0.7 mmHg (lit.) |
| Density | 1.017 g/mL at 20 °C (lit.) |
| Refractive Index | n |
| Storage Temp. | −20°C |
| UNSPSC | 12352100 |