N-Boc-1,2,3,6-tetrahydropyridine-4-boronic acid pinacol ester
ALDRICH/706531 - 95%
Synonym: (1-tert-
CAS Number: 286961-14-6
Empirical Formula (Hill Notation): C16H28BNO4
Molecular Weight: 309.21
MDL Number: MFCD03840345
Linear Formula: C16H28BNO4
Product Type: Chemical
| assay | 95% |
| form | powder |
| InChI | 1S/C16H28BNO4/c1-14(2,3)2 |
| InChI key | VVDCRJGWILREQH-UHFFFAOYSA |
| mp | 100-114 °C |
| SMILES string | CC(C)(C)OC(=O)N1CCC(=CC1) |
| Application: | Reagent used for • Suzuki-Miyaura cross-coupling using palladium phosphine catalyst • Palladium-catalyzed ligand-controlled regioselective Suzuki coupling • Palladium-catalyzed Suzuki-Miyaura coupling • Suzuki coupling followed by iodolactonization reaction • Wrenchnolol derivative optimized for gene activation in cells Reagent used in Preparation of several enzymatic inhibitors and receptor ligands • Orally active anaplastic lymphoma kinase inhibitors • Oxazolecarboxamides as diacylglycerol acyltransferase-1 inhibitors for treatment of obesity and diabetes • 4-arylpiperidinyl amides and N-arylpiperidin-3-yl-cycl • Quinazoline analogs as glucocerebrosidase inhibitors with chaperone activity for treatment of Gaucher disease, a lysosomal storage disorder • Arylpiperazine and piperidine ethers as dual acting norepinephrine reuptake inhibitors and 5-HT1A partial agonists |
| General description: | Boc-THP-Bpin is frequently used in metal catalyzed cross-coupling reactions, such as Suzuki-Miyaura and Negishi couplings. |
| Packaging: | 1 g in glass bottle |
| Packaging: | 250 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 95% |
| mp | 100-114 °C |
| UNSPSC | 12352103 |