1-Hydroxybenzotriazole hydrate
ALDRICH/711489 - wetted with not less than 20 wt. % water, 97% dry basis
Synonym: HOBt Hydrate
CAS Number: 123333-53-9
Empirical Formula (Hill Notation): C6H5N3O · xH2O
Molecular Weight: 135.12 (anhydrous basis)
EC Number: 219-989-7
Linear Formula: C6H5N3O · xH2O
Product Type: Chemical
assay | 97% dry basis |
composition | Water content, ~20% |
form | powder |
InChI | 1S/C6H5N3O.H2O/c10-9-6-4- |
InChI key | PJUPKRYGDFTMTM-UHFFFAOYSA |
mp | 155-158 °C (lit.) |
quality | wetted with not less than 20 wt. % water |
reaction suitability | reaction type: Addition Reactions |
SMILES string | [H]O[H].On1nnc2ccccc12 |
solubility | DMF: 0.1 g/mL, clear |
Application: | 1-Hydroxybenzotriazole hydrate is used as an additive: • In the oligonucleotide couplings. • In the preparation of poly(ethylene glycol)methyl ether-grafted CTS (mPEG-g-CTS). 1-Hydroxybenzotriazole hydrate can also be used:• In the solid phase peptide synthesis on TCNEO(tetracyanoethylene oxide)-modified graphite. |
General description: | 1-Hydroxybenzotriazolehyd |
Packaging: | 50, 250 g in poly bottle |
Symbol | GHS02,GHS07 |
Signal word | Danger |
Hazard statements | H207 - H319 - H412 |
Precautionary statements | P210 - P212 - P230 - P233 - P280 - P370 + P380 + P375 - P501 |
Hazard Codes | F |
Risk Statements | 1-11-44 |
Safety Statements | 26-37-60 |
RIDADR | UN3474 - class 4.1 - PG 1 - 1-Hydroxybenzotriazole, monohydrate |
WGK Germany | nwg |
Flash Point(F) | Not applicable |
Flash Point(C) | Not applicable |
Supplemental Hazard Statements | EUH044 |
Purity | 97% dry basis |
mp | 155-158 °C (lit.) |
UNSPSC | 12352000 |