COMU®
ALDRICH/712191 - 97%
Synonym: (1-
CAS Number: 1075198-30-9
Empirical Formula (Hill Notation): C12H19F6N4O4P
Molecular Weight: 428.27
MDL Number: MFCD11975052
Linear Formula: C12H19F6N4O4P
Product Type: Chemical
12 Principles of Green Chemistry: Principle 3—Less Hazardous Chemical Syntheses. This product manufacturing process was designed with lesser toxicity to human health and the environment.
12 Principles of Green Chemistry: Principle 12—Inherently Safer Chemistry for Accident Prevention. This product utilizes safer chemistry to minimize the potential for chemical accidents, including releases, explosions and fires.
| application(s) | peptide synthesis |
| assay | ≥96.5% (TLC) |
| 96.5-103.5% (T) | |
| 97% | |
| form | crystals |
| functional group | amine |
| ester | |
| ether | |
| nitrile | |
| greener alternative category |  , Aligned |
| greener alternative product characteristics | Less Hazardous Chemical Syntheses Inherently Safer Chemistry for Accident Prevention Learn more about the Principles of Green Chemistry . |
| InChI | 1S/C12H19N4O4.F6P/c1-4-19 |
| InChI key | GPDHNZNLPKYHCN-DZOOLQPHSA |
| Quality Level | 100 |
| reaction suitability | reaction type: Coupling Reactions |
| SMILES string | F[P-](F)(F)(F)(F)F.CCOC(= |
| storage temp. | 2-8°C |
| sustainability | Greener Alternative Product |
| Application: | COMU – Safer and More Efficient Peptide Coupling Reagent Advantages • Equal or even superior performance to HATU • Non-explosive (does not contain benzotriazole moiety) • Suitable for solution phase & solid phase peptide synthesis • Utmost retention of configuration – low to non-existent racemization • High solubility and stability in typical solvents • Visual or colorimetric reaction monitoring possible • Easy removal of water-soluble by-products |
| Application: | Morpholine-Based Immonium and Halogenoamidinium Salts as Coupling Reagents in Peptide Synthesis  |
| General description: | We are committed to bringing you Greener Alternative Products, which adhere to one or more of The 12 Principles of Greener Chemistry. This product is a Safer, non-explosive and more effective replacement for Benzotriazole-Based peptide coupling reagents and thus aligns with "Less Hazardous Chemical Synthesis" and "Inherently Safer Chemistry for Accident Prevention". Click here for more information. |
| Legal Information: | COMU is a registered trademark of Luxembourg Bio Technologies Ltd. |
| Packaging: | 5, 25, 100 g in poly bottle |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥96.5% (TLC); 96.5-103.5% (T); 97% |
| Storage Temp. | 2-8°C |
| UNSPSC | 12352107 |