BrettPhos
ALDRICH/718742 - 98%
Synonym: 2-
CAS Number: 1070663-78-3
Empirical Formula (Hill Notation): C35H53O2P
Molecular Weight: 536.77
MDL Number: MFCD11973797
Linear Formula: C35H53O2P
Product Type: Chemical
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 718742-50G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 718742-25G
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 718742-100MG
This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 718742-500MG
12 Principles of Green Chemistry: Principle 1—Waste Prevention. This product has a smaller environmental footprint through reduction of waste in the manufacturing process.
12 Principles of Green Chemistry: Principle 2—Atom Economy. This product was designed to maximize the incorporation of all raw materials used in the manufacturing process.
| assay | 98% |
| form | solid |
| functional group | phosphine |
| greener alternative category |  , Re-engineered |
| greener alternative product characteristics | Waste Prevention Atom Economy Design for Energy Efficiency Learn more about the Principles of Green Chemistry . |
| greener alternative product score | old score: 8 new score: 1 Find out more about DOZN™ Scoring |
| InChI | 1S/C35H53O2P/c1-23(2)26-2 |
| InChI key | WDVGNXKCFBOKDF-UHFFFAOYSA |
| mp | 187-195 °C |
| Quality Level | 300 |
| reaction suitability | reaction type: Cross Couplings |
| reagent type: ligand reaction type: Buchwald-Hartwig Cross Coupling Reaction |
|
| reagent type: ligand reaction type: Fluorinations |
|
| SMILES string | COc1c(P(C2CCCCC2)C3CCCCC3 |
| sustainability | Greener Alternative Product |
| Application: | Buchwald Phosphine Ligands for chemical Synthesis |
| Application: | BrettPhos is a dialkylbiaryl phosphine ligand developed by the Buchwald group. It promotes cross-coupling reactions more efficiently and exhibits improved reactivity compared to other catalytic systems. It can be used in:• palladium-catalyzed trifluoromethylation of aryl chlorides • Buchwald-Hartwig amination • synthesis of 4-aryl and alkyl substituted, N6-alkylated pyridazine-3,6-diamines via a Buchwald protocol For small scale and high throughput uses, product is also available as ChemBeads (928348 ) |
| Features and Benefits: | • White crystalline solid • Air- and moisture-stable • Thermally stable • Highly efficient • Wide functional group tolerance • Excellent selectivity and conversion |
| General description: | We are committed to bringing you Greener Alternative Products, which adhere to one of the four categories of Greener Alternatives . This product belongs to category of Re-engineered products, showing key improvements in Green Chemistry Principles “Waste Prevention”, “Atom Economy” and “Design for Energy Efficiency”. Click here to view its DOZN scorecard. |
| Packaging: | 1, 5, 25, 50 g in glass bottle |
| Packaging: | 100, 500 mg in glass bottle |
| RIDADR | NONH for all modes of transport |
| WGK Germany | nwg |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 98% |
| mp | 187-195 °C |
| UNSPSC | 12352112 |