(4S)-2-[2-(diphenylphosphino)phenyl]-4,5-dihydro-5,5-dimethyl-4-(1-methylethyl)-oxazole
ALDRICH/719641 - 97%
Synonym: (S)
CAS Number: 1152313-76-2
Empirical Formula (Hill Notation): C26H28NOP
Molecular Weight: 401.48
MDL Number: MFCD16621462
Linear Formula: C26H28NOP
Product Type: Chemical
| assay | 97% |
| form | solid |
| InChI | 1S/C26H28NOP/c1-19(2)24-2 |
| InChI key | JGUZEKBWCGNHHN-DEOSSOPVSA |
| mp | 124-128 °C |
| SMILES string | CC(C)[C@@H]1N=C(OC1(C)C)c |
| Application: | (S)-5,5-(Dimethyl)-i-Pr-PHOX is a phosphinooxazoline ligand (PHOX), belongs to the class of non-C2 symmetric chiral ligand. It can be used in: • The enantioselective Pd-catalyzed allylation reactions. • The synthesis of (R)-2-phenyl-2,5-dihydrofur • The allylation reaction of fluorinated allyl enol carbonates and fluorinated silyl enol ethers to prepare allylated tert α-fluoroketones. |
| Application: | Use of 5,5-(Dimethyl)-i-Pr-PHOX as a Practical Equivalent to t-Bu-PHOX in Asymmetric Catalysis   Design, Synthesis, and Applications of Potential Substitutes of t-Bu-Phosphinooxazoline in Pd-Catalyzed Asymmetric Transformations and Their Use for the Improvement of the Enantioselectivity in the Pd-Catalyzed Allylation Reaction of Fluorinated Allyl Enol Carbonates |
| Packaging: | 500 mg in glass bottle |
| Symbol |  GHS06 |
| Signal word | Danger |
| Hazard statements | H301 - H315 - H319 - H335 - H413 |
| Precautionary statements | P273 - P301 + P310 + P330 - P302 + P352 - P305 + P351 + P338 |
| Hazard Codes | T |
| Risk Statements | 25-36/37/38-53 |
| Safety Statements | 26-45 |
| RIDADR | UN 2811 6.1 / PGIII |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | 97% |
| mp | 124-128 °C |
| UNSPSC | 12352005 |