tBuBrettPhos

ALDRICH/730998 - 97%

Synonym: t-Bu Brett Phos; t-BuBrett-Phos; tertButylBrettPhos; 2-(Di-tert-butylphosphino)-2′,4′,6′- triisopropyl-3,6-dimethoxy-1,1′-biphenyl; t-BuBrett Phos; t-BuBrettPhos; [3,6-Dimethoxy-2′,4′,6′-tris(1-methylethyl) [1,1′-biphenyl]-2-yl]bis(1,1-dimethylethyl)phosphine; tert-ButylBrettPhos

CAS Number: 1160861-53-9
Empirical Formula (Hill Notation): C₃₁H₄₉O₂P
Molecular Weight: 484.69
MDL Number: MFCD13181930
Linear Formula: C₃₁H₄₉O₂P
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-730998-100MG	100 mg	$166.00 1/EA	Add To Favorites
45-730998-500MG	500 mg	$222.00 1/EA	Add To Favorites
45-730998-1G	1 g	$303.00 1/EA	Add To Favorites
45-730998-5G	5 g	$1070.00 1/EA	Add To Favorites
45-730998-50G	50 g	$6350.00 1/EA	Add To Favorites

This picture is provided solely for illustration purposes. Optical properties of the actual product may deviate. Relevant product information is printed on labeled products and other accompanying or available information material. This image depicts SKU: 730998-50G

Properties
Descriptions
Safety Info.
Basic Data

assay	97%
form	solid
functional group	phosphine
InChI	1S/C31H49O2P/c1-19(2)22-17-23(20(3)4)27(24(18-22)21(5)6)28-25(32-13)15-16-26(33-14)29(28)34(30(7,8)9)31(10,11)12/h15-21H,1-14H3
InChI key	REWLCYPYZCHYSS-UHFFFAOYSA-N
mp	166-170 °C
Quality Level	300
reaction suitability	reaction type: Cross Couplings
	reagent type: ligand reaction type: Arylations
	reagent type: ligand reaction type: Buchwald-Hartwig Cross Coupling Reaction
	reagent type: ligand reaction type: C-X Bond Formation
	reagent type: ligand reaction type: Fluorinations
SMILES string	COc1ccc(OC)c(c1P(C(C)(C)C)C(C)(C)C)-c2c(cc(cc2C(C)C)C(C)C)C(C)C

Application:	Buchwald Phosphine Ligands for chemical Synthesis
Application:	Common applications • Buchwald-Hartwig amination and C-O coupling • Suzuki, Negishi, Stille, Hiyama, Sonogashira cross-couplings • α-Arylation reaction New Applications: • Conversion of aryl and vinyl triflates to bromides and chlorides • Conversion of aryl triflates to aryl fluorides • O-Arylation of ethyl acetohydroximate • Conversion of aryl chlorides and sulfonates to nitroaromatics
Features and Benefits:	• White crystalline solid • Air- and moisture-stable • Thermally stable • Highly efficient • Wide functional group tolerance • Excellent selectivity and conversion
General description:	tBuBrettPhos is a dialkylbiaryl phosphine ligand developed by the Buchwald group . It promotes cross-coupling reactions more efficiently and exhibits improved reactivity compared to other catalytic systems. tBuBrettPhos is a phosphine ligand widely used in palladium-catalyzed cross-coupling reactions.
Legal Information:	Usage subject to US Patent 7,858,784
Packaging:	1, 5, 50 g in glass bottle
Packaging:	100, 500 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	97%
mp	166-170 °C
UNSPSC	12352112

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