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Nordihydroguaiaretic acid

ALDRICH/74540 - ≥97.0% (HPLC)

Synonym: 1,4-Bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane; 4,4′-(2,3-Dimethyltetramethylene)dipyrocatechol; Masoprocol; NDGA

CAS Number: 500-38-9
Empirical Formula (Hill Notation): C18H22O4
Molecular Weight: 302.36
EC Number: 207-903-0
MDL Number: MFCD00002206
Linear Formula: [-CH(CH3)CH2C6H3-1,2-(OH)2]2
Product Type: Chemical
Catalog Number PKG Qty. Price Quantity
45-74540-1G 1 g
 $108.00
1/EA		 Add To Favorites
45-74540-5G 5 g
 $416.00
1/EA		 Add To Favorites

 

assay ≥97.0% (HPLC)
form crystals
impurities ≤2% water
InChI 1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3
InChI key HCZKYJDFEPMADG-UHFFFAOYSA-N
mp 184-186 °C (lit.)
Quality Level 100 
SMILES string CC(Cc1ccc(O)c(O)c1)C(C)Cc2ccc(O)c(O)c2
Application: Nordihydroguaiaretic acid can be used:
• In the synthesis of nordihydroguaiaretic acid derivatives with potent HIV inhibition activity.
• As a starting material in the synthesis of tetra-O-methylnordihydroguaiaretic acid.
Biochem/physiol Actions: Lipoxygenase inhibitor; polyphenol-bearing o-dihydroxy (catechol) structure.
General description: Nordihydroguaiaretic acid (NDGA) is used as an antioxidant and potent scavenger of reactive oxygen species (ROS).
Other Notes: Inhibitor of broad bean lipoxygenase
Packaging: 1, 5 g in glass bottle
Purity ≥97.0% (HPLC)
mp 184-186 °C (lit.)
UNSPSC 12352100

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