Sodium difluoroheptylazidosulfinate

ALDRICH/746118 - 95%

Synonym: Baran DAAS-Na Reagent; Sodium 1,1-difluoro-7-azido-heptylsulfinate; Sodium 7-azido-1,1-difluoroheptanesulfinate

CAS Number: 1450912-63-6
Empirical Formula (Hill Notation): C₇H₁₂F₂N₃NaO₂S
Molecular Weight: 263.24
Linear Formula: C₇H₁₂F₂N₃NaO₂S
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-746118-100MG	100 mg	$316.00 1/EA	Add To Favorites

Baran Diversinate for Late-Stage Functionalization

Properties
Descriptions
Safety Info.
Basic Data

assay	95%
form	solid
InChI	1S/C7H13F2N3O2S.Na/c8-7(9,15(13)14)5-3-1-2-4-6-11-12-10;/h1-6H2,(H,13,14);/q;+1/p-1
InChI key	FFNHIEJQAMGBCZ-UHFFFAOYSA-M
reaction suitability	reaction type: C-C Bond Formation
	reagent type: catalyst reaction type: C-H Activation
	reagent type: linker
SMILES string	[Na+].[O-]S(=O)C(F)(F)CCCCCCN=[N+]=[N-]
storage temp.	2-8°C

Application:

Within heteroarene platforms, DAAS-Na allows for the direct introduction of a difluoroalkyl chain carrying an azide group, which is designed for the purpose of bioconjugation. Through a Huisgen cycloaddition (a "click" reaction), the azide moiety can then be reacted with a terminal alkyne that is bound to a functional molecule such as biomacromolecules. This effectively allows for a covalent linkage between a heteroarene and any target molecule, for example, between a heteroarene-containing drug and an antibody. This reagent was developed by the Baran Group and is one of several reagents for the direct alkylation of heterocycles.

Learn More at the Professor and Product Portal External link

of Professor Phil S. Baran.

Packaging:

100 mg in glass insert

Symbol	GHS07
Signal word	Warning
Hazard statements	H315 - H319 - H335
Precautionary statements	P302 + P352 - P305 + P351 + P338
Hazard Codes	Xi
Risk Statements	36/37/38
Safety Statements	26
RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

Purity	95%
Storage Temp.	2-8°C
UNSPSC	12352125

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