SPhos Pd G2

ALDRICH/753009

Synonym: 2nd Generation SPhos Precatalyst; Chloro(2-dicyclohexylphosphino-2′,6′-dimethoxy-1,1′-biphenyl)[2-(2′-amino-1,1′-biphenyl)]palladium(II); SPhos-Pd-G2

CAS Number: 1375325-64-6
Empirical Formula (Hill Notation): C₃₈H₄₅ClNO₂PPd
Molecular Weight: 720.62
MDL Number: MFCD20264897
Linear Formula: C₃₈H₄₅ClNO₂PPd
Product Type: Chemical

Catalog Number	PKG Qty.	Price


45-753009-250MG	250 mg	$66.50 1/EA	Add To Favorites
45-753009-1G	1 g	$185.00 1/EA	Add To Favorites
45-753009-5G	5 g	$589.00 1/EA	Add To Favorites

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Properties
Descriptions
Safety Info.
Basic Data

feature	generation 2
form	solid
functional group	phosphine
InChI	1S/C26H35O2P.C12H10N.ClH.Pd/c1-27-23-17-11-18-24(28-2)26(23)22-16-9-10-19-25(22)29(20-12-5-3-6-13-20)21-14-7-4-8-15-21;13-12-9-5-4-8-11(12)10-6-2-1-3-7-10;;/h9-11,16-21H,3-8,12-15H2,1-2H3;1-6,8-9H,13H2;1H;/q;;;+1/p-1
InChI key	NOMWEFBAPVZIIP-UHFFFAOYSA-M
mp	218 °C (dec.)
reaction suitability	core: palladium
	reaction type: Buchwald-Hartwig Cross Coupling Reaction
	reaction type: Heck Reaction
	reaction type: Hiyama Coupling
	reaction type: Negishi Coupling
	reaction type: Sonogashira Coupling
	reaction type: Stille Coupling
	reaction type: Suzuki-Miyaura Coupling
	reagent type: catalyst reaction type: Cross Couplings
SMILES string	COC1=CC=CC(OC)=C1C2=C(P(C3CCCCC3)C4CCCCC4)C=CC=C2.NC5=C(C6=C([Pd]Cl)C=CC=C6)C=CC=C5

Application:	Application in Suzuki-Miyaura coupling: • Self-arylation of 1-alkyl-3-bromo-2-phenyl-2,1-borazaronaphthalenes to form 2,1-borazaronaphthols. • Suzuki–Miyaura coupling of [Ru(bpy)₂]⁺ with 4-carboxyphenylboronic acid. • Suzuki–Miyaura coupling of β-borylated porphyrins with 2-iodoaniline.
General description:	SPhos Pd G2 is a second generation (G2) precatalyst in which phenethylamine based backbone of the (G1) complex is substituted with a biphenyl-based ligand. This improvement on the previous generation allows creating the active palladium species at room temperature with weak phosphate or carbonate bases. The catalyst proves remarkably adept at achieving a variety of Suzuki-Miyaura couplings among other cross-coupling reactions.
Packaging:	1, 5 g in glass bottle
Packaging:	250 mg in glass bottle

RIDADR	NONH for all modes of transport
WGK Germany	WGK 3
Flash Point(F)	Not applicable
Flash Point(C)	Not applicable

mp	218 °C (dec.)
UNSPSC	12161600

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