5-(Benzylthio)-1H-tetrazole
ALDRICH/75666 - ≥99.0% (HPLC)
Synonym: 5-
CAS Number: 21871-47-6
Empirical Formula (Hill Notation): C8H8N4S
Molecular Weight: 192.24
MDL Number: MFCD00068731
Linear Formula: C8H8N4S
Product Type: Chemical
| assay | ≥99.0% (HPLC) |
| form | crystals |
| InChI | 1S/C8H8N4S/c1-2-4-7(5-3-1 |
| InChI key | GXGKKIPUFAHZIZ-UHFFFAOYSA |
| mp | 135-138 °C (DSC-onset) |
| SMILES string | C(Sc1nnn[nH]1)c2ccccc2 |
| General description: | 5-(Benzylthio)-1H-tetrazole (BTT activator) is an organic compound that is used as an activator in the synthesis of oligonucleotides. The activator reacts with the phosphoramidite group to form a highly reactive intermediate. The intermediate then forms an internucleotide bond with the detritylated 5′-hydroxyl group of the growing oligonucleotide chain. |
| Other Notes: | Activator for DNA synthesis; superior alternative to tetrazole |
| Packaging: | 5 g in poly bottle |
| Symbol |   GHS05,GHS07 |
| Signal word | Danger |
| Hazard statements | H315 - H318 - H335 |
| Precautionary statements | P280 - P302 + P352 - P305 + P351 + P338 + P310 |
| Hazard Codes | Xi |
| Risk Statements | 36/37/38 |
| Safety Statements | 26 |
| RIDADR | NONH for all modes of transport |
| WGK Germany | WGK 3 |
| Flash Point(F) | Not applicable |
| Flash Point(C) | Not applicable |
| Purity | ≥99.0% (HPLC) |
| mp | 135-138 °C (DSC-onset) |
| UNSPSC | 12352100 |